Sheldon: Is anyone else troubled by the Spider-Man theme song?
Leonard: Why would it trouble you? It's like your third favorite cartoon theme song.
Sheldon: It is, right behind [Sheldon sings "Inspector Gadget" and "Teenage Mutant Ninja Turtles" theme songs]
Sheldon: However, the Spider-Man lyrics posit that Spider-Man's Spider-Man does whatever a spider can.
Howard: Yeah, so?
Sheldon: I can think of many things that Spider-Man can't do that a spider can. One crawl in your ear and die, two legally leave Guatemala without a passport, and three have sex with a spider.

Howard: Boy, we're married to a couple of ball busters, huh, Mike?
Bernadette's Dad: That's my wife and daughter you're talking about.
Howard: Great couple of gals.
Bernadette's Dad: I wouldn't go that far.

Death by chicken. That's a pretty fowl way to go.

Howard: Well, we appear to have reached an impasse. And, you know, I have to say, I thought you'd be more upset that your laptop is sitting on my junk.
Raj: I didn't pick up on that. That's a nice touch.

Howard: Meanwhile, you still don't have a car.
Sheldon: Don't try to change the subject. This is about a parking space. It has nothing to do with cars.

Howard: Do you expect me to build this?
Sheldon: I expect you to wipe the pudding off your chin. Gentlemen.

Howard: Boy, if these walls could talk.
Leonard: They'd say, "Why does he touch himself so much?"
Howard: Yeah.

Howard: So, this one's on God.
Bernadette: That might be a little more convincing if you didn't have a mouth full of bacon cheeseburger.
Howard: My religion's kinda loosey-goosy. Basically, as long as you have your schmekel clipped and don't wear a cross, you're good.

There's the problem. You can't beat Hawking like that. He hates to lose. Everyone knows the guy's a big baby. I mean, forget the wheelchair, he should be in a stroller.

Howard: Two weeks ago I was an astronaut.
Bernadette: Yeah, well, now you're a Smurf. Keep walking.

You know, people say the Soyuz capsule was a lemon. But, hey, that baby got me to space and back.

At least my mother made her boyfriend climb out the window.

TBBT Quotes

Penny: Here's a question-- as an alien pretending to be human, are you planning to engage in any post-prom mating rituals with Amy?
Sheldon: There are post-prom mating rituals?
Penny: Not always. Unless your date drives a van with an air mattress, then always.
Sheldon: Well, if it's part of the prom experience, then I'm open to it.
Penny: You're kidding.
Sheldon: I may be an alien, but I have urges.If Amy wants to copulate by firing her eggs into space, well, then, I will happily catch them with the reproductive sac on my upper flermin. I'm not the best at reading facial cues, but I can see that you're a little turned on.

Raj: Well, to paraphrase Shakespeare: It's better to have loved and lost than to stay home every night and download increasingly shameful pornography.
Penny: Oh... you poor baby.
Raj: What's wrong with me, Penny?
Penny: Nothing, nothing. You know, if we weren't friends - and you hadn't brought up that creepy pornography story - I'd be on you like the speed of light squared on matter to make energy.
Raj: Hey, you totally got that right. E = MC squared.
Penny: I listen. I have no idea what it means, but I listen.