Leonard: Does your family have a history of heart disease?
Wolowitz: My family is the history of heart disease. There's a cave painting in France of one of my ancestors doing this. [mimicks heart attack]

Have you told your parents you're dating this short glass of skim milk?

Her freakishly small hands make anything look big. That's one of the reasons I love her.

Believe in magic, you Muggle!

That crazy bastard is looking at quirky in the rear view mirror.

I think it's like Beetlejuice. We said his name too many times.

Leonard: Still arguing which is the best CSI?
Howard: We agreed they all have their merits.

Howard: I'm not having this conversation with you Ma!
Howard's Ma: God forbid you get one of those new fancy sex diseases!

Bernadette: I think the woman can manage to put a wig on by herself.
Howard: It's not just the wig, it's pinning her hair up, it's putting on her eyebrows...it's a two person job.

Put your tie back in your pants.

Let's go smooch some rich, wrinkled toucas.

You take this one. I spent an hour last night on 'Why can't vampires shave when they can't see themselves in the mirror?'

TBBT Quotes

Sheldon: Are you still mad about the sperm bank?
Leonard: No!
Sheldon: Do you want to hear an interesting thing about stairs?
Leonard: Not really.
Sheldon: If the height of a single step is off by as little as two millimeters most people will trip.
Leonard: I don't care—two millimeters?! That doesn't seem right.
Sheldon: No, it's true! I did a series of experiments when I was twelve; my father broke his clavicle.

Penny, there's only one cookie with something in the middle that solves life's problems, and that's an Oreo. Or a Nutter Butter, if you're in a pinch.

Sheldon