I think it's nice. Your date. I think you and the pig murderer make a really good couple.

Alex: Listen. You had that heart patient and it reminded you of Denny and how bad you felt when you were lying on that bathroom floor. I get that! I get that you're scared. But you're not going to have to feel like that again. Because I'm not going to die, Izz. And I'm not gonna cheat on you, and I'm not gonna go anywhere! 'Cause, I think you're my best shot at... I think with you... you make me better. You make me wanna BE better. You make me want to be good. And I think I can. With you. I think I can. So I'm not going anywhere, and you can stop hiding. And if you wanna be scared that's okay just be scared with me. Be scared while you scrub in with me on my first solo surgery. Okay?
Izzie: You love me.
Alex: Shut up. [kisses her, leaves] Solo surgery!
Denny: I'm really starting to not like that guy.

Alex: I love you! I frickin' love you. I just got the solo surgery and the first thing I did was look for you. And you weren't there. You're never there anymore. And I was thinking about it and I think it might be because you love me too. And because you're scared of that. And because I... I screwed it up last time, and because... Denny died, and-
Izzie: Alex...

Alex: Izz... I won!
Izzie: Hey. What time is it?
Alex: Yang. She picked me for the solo surgery.
Izzie: She did? That's amazing.
Alex: I love you!
Izzie: What?

Alex: When I win, you can scrub in for me.
Izzie: Alex, she's... she's not gonna pick you.
Alex: I'll scrub in for you too if you win, which you won't, 'cause I will. [kisses her]
Denny: Enough!
Izzie: I... I gotta go!

George: Are you coming? We gotta do clinic. Flu season fun!
Izzie: Um, yeah ... I ... will catch up with you.
Denny: Me too.
Izzie: Shut up.
George: [stares, confused]
Izzie: Not you.

Izzie: I'm sorry ... I can't.
Denny: It's okay. I'll be right here.

Alex: Gonna try to get some sleep. I gotta be back to the hospital in six hours.
Izzie: Alex wait. I'm a mess. I'm a frickin' mess and I know that and, I ... you deserve better.
Alex: Stop it. If you don't want to be with me, if this is too much for you right now, it's okay. But you're gonna have to break up with me, because I'm not going anywhere. I can handle the mess. It's up to you.

Denny: Izzie... stop freaking out.
Izzie: You're not real. You're not real.
Denny: Hey, I told you.
Izzie: You're not real! You're not real! You're not real!
Denny: Look at me. Touch me.

Izzie: I said goodbye. I burned the sweater!
Denny: Yeah, thanks for that, by the way. I loved that sweater. You made me that sweater!

Erica: I'm gonna stop you right there. Look. I don't get attached to patients. But I like this guy, and I've spent almost two years giving him hope, and then taking it away. This procedure will buy him time until he can get another shot at a transplant. We need to make sure it works, okay?
Meredith: Absolutely.
Izzie: Of course.

Erica: Have you familiarized yourself with the case?
Meredith: Michael Morris, 44-year-old male with congenital hypertrophic cardio myopathy. Failed medical treatment at Seattle West. Been waiting on a heart transplant since narrowly missing out on one on May 14 of Two Thousand and ...
Izzie: Wait... May 14 what?
Meredith: What?
Izzie: That's Denny's heart. That's the heart I stole for Denny.

Grey's Anatomy Quotes

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.

Meredith

Callie: Did anyone ever think you two were a couple?
Meredith: No, because we screw boys like whores on tequila.
Cristina: Then we either try to marry them or drown ourselves.
Callie: Huh.