Give me back my surgery or I'll shoot your ass off!

Izzie

People are terrible to the people they love sometimes. They're mean. You were both having a hard time and you took it out on each other. It doesn't make you the worst wife in the world. It just makes you a person who made a mistake.

Cristina: We are not happy, glowy people.
Izzie: Yeah.
Cristina: We need to get out of here.
Meredith: Yeah

Alex: You stole my surgery!
Izzie: Using me as a doormat is one thing. Screwing with my career is another! I have been wiping your snot and covering your ass for weeks now. And all you've done is abuse me. And for a little while you get to do that because you're heartbroken and pathetic, and I'm a good friend. But it ends now. Get your own surgery and wipe your own snot.

Derek: I'd like to buy these two a drink.
Izzie: You are the best roommate ever!
Derek: I am. Just to be clear, if you two ever pull any of that crap with one of my cases again, I will have you thrown out of the program.

Izzie: Son of a bitch.
Alex: Go cry to somebody who cares.

Izzie: Dr. Shepherd, I want back on this case. Alex stole him from me. Remember when I was telling you that-
Derek: Dr. Stevens let's be clear. In this hospital, I am not your roommate, I don't give a crap about your personal problems. I have a resident, I don't need another one.

Izzie: What are you doing in here?
Derek: I was thinking about making this my office when you move out.
Izzie: When I move out? When am I moving out?
Derek: Oh. Soon?

Eat the muffin, Mer. Taste the muffin. Remember. The muffin.

Izzie: What did you say to Alex?
Meredith: I... I didn't say anything. I just said it's nice that you two are friendly again.
Izzie: Ugh! Meredith why can't you just mind your own business? I mean... you know what forget it! I should never have told you anything! You can't keep anything to yourself unless it's for Cristina.
Meredith: Izzie!
Derek: Marriage?
Meredith: Not funny!

Izzie: See? I told you I would show you my dress.
Denny: You look better than a bride.

Meredith: I'm sorry about chasing Alex.
Izzie: I forgive you.

Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

I want to marry you. I want to have kids with you. I want to build us a house. I want to settle down and grow old with you. I want to die when I'm 110 years old, in your arms. I don't want 48 uninterrupted hours. I want a lifetime. Mmm. Do you see what happens? I say things like that and you fight the urge to run in the opposite direction. It's okay, I understand. I didn't, but now I do, I do. You're just getting started and I've been doing this for a long time now. Deep down, you're still an intern, and you're not ready.

Derek