Give me back my surgery or I'll shoot your ass off!

Izzie

People are terrible to the people they love sometimes. They're mean. You were both having a hard time and you took it out on each other. It doesn't make you the worst wife in the world. It just makes you a person who made a mistake.

Cristina: We are not happy, glowy people.
Izzie: Yeah.
Cristina: We need to get out of here.
Meredith: Yeah

Alex: You stole my surgery!
Izzie: Using me as a doormat is one thing. Screwing with my career is another! I have been wiping your snot and covering your ass for weeks now. And all you've done is abuse me. And for a little while you get to do that because you're heartbroken and pathetic, and I'm a good friend. But it ends now. Get your own surgery and wipe your own snot.

Derek: I'd like to buy these two a drink.
Izzie: You are the best roommate ever!
Derek: I am. Just to be clear, if you two ever pull any of that crap with one of my cases again, I will have you thrown out of the program.

Izzie: Son of a bitch.
Alex: Go cry to somebody who cares.

Izzie: Dr. Shepherd, I want back on this case. Alex stole him from me. Remember when I was telling you that-
Derek: Dr. Stevens let's be clear. In this hospital, I am not your roommate, I don't give a crap about your personal problems. I have a resident, I don't need another one.

Izzie: What are you doing in here?
Derek: I was thinking about making this my office when you move out.
Izzie: When I move out? When am I moving out?
Derek: Oh. Soon?

Eat the muffin, Mer. Taste the muffin. Remember. The muffin.

Izzie: What did you say to Alex?
Meredith: I... I didn't say anything. I just said it's nice that you two are friendly again.
Izzie: Ugh! Meredith why can't you just mind your own business? I mean... you know what forget it! I should never have told you anything! You can't keep anything to yourself unless it's for Cristina.
Meredith: Izzie!
Derek: Marriage?
Meredith: Not funny!

Izzie: See? I told you I would show you my dress.
Denny: You look better than a bride.

Meredith: I'm sorry about chasing Alex.
Izzie: I forgive you.

Grey's Anatomy Quotes

[narrating] "At the end of the day, when it comes down to it, all we really want is to be close to somebody. So this thing where we all keep our distance and pretend not to care about each other, it's usually a load of bull. So we pick and choose who we want to remain close to, and once we've chosen those people, we tend to stick close by. No matter how much we hurt them. The people that are still with you at the end of the day, those are the ones worth keeping. And sure, sometimes close can be too close. But sometimes, that invasion of personal space, it can be exactly what you need."

MEREDITH

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)