Oooh! A trauma!

Cristina: "Only three points for watching. You gotta do."
Izzie: "I DO do!"

Lexie: I never knew what to say to them. In high school. Kids like him. They were always so... separate from the rest of us, you know, alone. It wasn't like that for me. I was prom queen and class valedictorian.
Izzie: Yeah, I wouldn't broadcast that.

Izzie: Do you want me to keep the family informed?
Erica: I want you to think like a surgeon. You're thinking like a social worker. If you wanna be a social worker you can save yourself a lot of effort because the training is two years not 12. If you wanna be a surgeon, you can update the family when the crisis has passed.

Meredith: Hey, you guys....
Izzie: You can't call dibs on a human being.
Meredith: You guys, I think we should move.
Cristina: Let go of the gurney.
Izzie: YOU let go.
Meredith: Move!!!

I'm so sick of Meredith and Cristina and their stupid love affair with each other that they have to rub in everyone's faces.

I'm going to go in early. I'm going to get on hard-core, Erica Hahn cardio and I'm gonna kick ass at it. And when I kick ass at cardio, it's going to piss Cristina off, but it won't matter, because I'll be a kick-ass cardio god!

Izzie: I'm in love with this incredible guy and we're having problems. And my best friend, he would know what to say to me about it. I need to be able to talk to my best friend. I cannot get through this without my best friend.
George: Why isn't this easier?
Izzie: I don't know.
George: Well, I want my best friend back.
Izzie: Me too.

Girl 2: I'm gonna write a letter to his mom and dad.
Girl 1: That's really beautiful.
Girl 2: Yeah.
Izzie: Get out.
Girl 2: What?
Izzie: Get out. You're not even supposed to be in here.
Girl 2: She's here.
Izzie: She's his friend. His best friend. Go away. Go!
Marissa: I'm sorry. I didn't mean to ...
Izzie: It's okay. You just lost your best friend. It's... it's the worst thing in the world.

Girl 1: This is so sad. I used to walk by his house everyday.
Girl 2: He was in my algebra class... I think.
Izzie: Marissa, I know that this seems impossible right now, but you will get through this. Danny would have wanted you to.
Marissa: You don't know what he would have wanted. You're just like them. You're a prom queen and you're trying to act like you know what it's like for me. You have no idea what it's like.
Izzie: I wasn't a prom queen. I was the girl in the cheap clothes from the trailor park who got pregnant. I got thrown in the pregnant girls class. None of the mothers would let their kids hang out with me. But I got through it. You will get through this.

I love George. Oh, God I do, I love him, and I'm so happy because he's kind and smart and um, sweet and sexy. He's perfect, perfect, except for the fact that he kisses like a chicken. You know a chicken pecking the ground for food, justs pecking and pecking and pecking, and when he's pecking at me like that I forget that I love him, I forget that he's kind and sweet and sexy and I just wanna scream, "Stop pecking at me!" Did he peck you like a chicken, Mer?

Izzie: This is absurd.
George: Hey...
Izzie: You shouldn't be sleeping in the On-Call room.

Grey's Anatomy Quotes

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.

Meredith

Callie: Did anyone ever think you two were a couple?
Meredith: No, because we screw boys like whores on tequila.
Cristina: Then we either try to marry them or drown ourselves.
Callie: Huh.