Just when we think we figured things out, the universe throws us a curveball. So, we have to improvise. We find happiness in unexpected places. We find ourselves back to the things that matter the most. The universe is funny that way. Sometimes it just has a way of making sure we wind up exactly where we belong.

Judge: Applicants Grey and Shepherd...
Derek: That'd be us.
Judge: I need to see some ID. OK, this seems to be in order, I'll jump right in. We are here today to participate in a marital union...
Bailey: To celebrate love and happiness and loyalty, and in my opinion, a little bit of magic.
Judge: In the form and regulations of the state of Washington,
Bailey: To bring together two exceptional and beautiful human beings
Judge: Since it is your intention to enter into marriage, join hands, and repeat after me. I, Derek Shepherd...
Derek: I, Derek Shepherd
Arizona: I take you, Calliope Torres to be my wife.
Meredith: For better or for worse in good times and in bad
Callie: I choose you to be the one whom I spend my life
Arizona: I love you.
Callie: I love you.

Derek: Let's adopt this baby.
Meredith: What? Are you serious?

Cristina: Well, he only has a shot because I've been benched. The playing field has been leveled. You're all welcome.
Meredith: My Alzheimer's trial kicks African orphanage ass. It kicks all your asses.

Diseases. Toxins. Our bodies encounter dangers all the time. Just beneath the surface hidden. Whether you realize it or not, your body is constantly protecting itself. Every time you blink your eye, you wash away thousands of unwanted microbes. Breathe in too much unwanted pollen, and you sneeze. The body detects the invader. It releases its white blood cells, and it attacks.

After a trauma, your body is at its most vulnerable. Response time is critical. So you're suddenly surrounded by people—doctors, nurses, specialists, technicians—surgery is a team sport. Everyone pushing for the finish line. Putting you back together again. But surgery is a trauma in and of itself, and once it's over, the real healing begins. It's called recovery. Recovery is not a team sport. It's a solitary distance run. It's long. It's exhausting. And it's lonely as hell.

The length of your recovery is determined by the extent of your injuries. And it's not always successful. No matter how hard we work at it. Some wounds might never fully heal. You might have to adjust to a whole new way of living. Things may have changed too radically to ever go back to what they were. You might not even recognize yourself. It's like you haven't recovered anything at all. You're a whole new person with a whole new life.

Derek: Meredith i am so sorry. Addison...what are you doing here?
Addison: You'd know if you'd bother to answer any one of my phone calls. (turns to Meredith) Hi. I'm Addison Shepherd
Meredith: Shepherd?
Addison: And you must be the woman who's been screwing my husband.

If you can think of a reason; any reason at all why the universe is so screwed up and random and mean; now would be an amazingly good time to tell me because I really need some answers.

Yesterday at that baby shower, I was jealous of Callie because she got pregnant without trying. And we tried. I get shots, I take my temperature, I put my legs in the air, and nothing. The universe says screw you Meredith and gives Callie a kid and then puts Callie through a windshield. I mean what the hell is going on? What's the point?

Cristina: Yesterday we were at her stupid baby shower.
Meredith: I take it back. You can be Callie's baby's god-mother.
Alex: If there's a baby to god-mother.

Meredith: I can't get over the fact that you know what onesie-decorating is.
Mark: I've been boning up. That's what you do for the people you love.
Arizona: Oh, bite me, Mark.

Grey's Anatomy Quotes

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.

Meredith

Doesn't matter how tough we are, trauma always leaves a scar. It follows us home, it changes our lives, trauma messes everybody up, but maybe that's the point. All the pain and the fear and the crap. Maybe going through all of that is what keeps us moving forward. It's what pushes us. Maybe we have to get a little messed up, before we can step up.

Alex (narrating)