Penny: I cannot believe we were missing that jerk.
Sheldon: You were.

Penny: I'm calling him.
Sheldon: Oh, goodie! Put him on speaker phone.

Raj: I haven't had a drink since last night.
Penny: You're talking to me.
Raj: I am. And, now I'm crying for a whole different reason.

Penny: I love you.
Leonard: I love you, too.

Penny: Oh gosh, Sheldon, the genius, is jealous of Leonard.
Sheldon: I'm not jealous. I'm just very unhappy that good things are happening for him and not happening for me.

Bernadette: You know, one of the things that helped me get through Howard being in space for so long was getting married before he left.
Penny: Bernadette, sweetie, shut up.

Penny: Oh, I don't know. Remember what happened when I took care of your goldfish?
Leonard: Well, flush Sheldon down the toilet and get me a new one.

Oh, sweetie, if you're gonna screw things up, it's gonna be while you're here, not while you're away.

Penny: On a ship? Aren't they afraid Hawking will just roll overboard?
Leonard: Uh, he's not gonna be there. He's just sending a team to research his theory.
Penny: Oh sure. Like when you send me to kill spiders in your bathtub.

Penny: This isn't alcohol. It's a potion that makes me like you.
Leonard: Double potion, please.

Oh, it's not so bad. You lost money, you're filled with shame, and you got groped by a stranger. That's Vegas. You nailed it.

Penny: Vegas here we come.
Bernadette: No husbands. No boyfriends. No rules
Amy: No rules. We're not going to get drunk and have a six-way with the Blue Man Group, are we?
Penny: No.
Amy: So there are some rules.
Bernadette: Okay. No husbands. No boyfriends. Some rules.
Amy: Thank you. VEGAS!

TBBT Quotes

Penny, there's only one cookie with something in the middle that solves life's problems, and that's an Oreo. Or a Nutter Butter, if you're in a pinch.

Sheldon

Leonard: Hi. I'm Leonard. You are beautiful. You pop, sparkle and buzz electric. I'm going to pick you up at eight, show you a night you will never forget.
Raj: Where are we going?