PRESTON: "Look, I know this is test day and I'm not supposed to be talking about the wedding on test day, but since tomorrow's our wedding day..."
CRISTINA: "You have five seconds. Go."
PRESTON: "Bill Adams can't make it. I have no best man."
CRISTINA: "Oh, no, baby, I'm sorry."
PRESTON: "And I need your vows -"
CRISTINA: "Okay. Time's up!"

RICHARD: "Go away!"
ADDISON: "But we can help!"
PRESTON: [to Addison] "No, WE can help."
ADDISON: "What's that supposed to mean?"
PRESTON: "He doesn't have any woman parts."
ADDISON: "Irrelevant."

PRESTON: "What was that?"
CRISTINA: "You’re gonna have to put up with me being…nice and sweet for a little while."
PRESTON: "That’ll be a nice change of pace."
CRISTINA: "Shut up."
PRESTON: "That’s more like it."

DEREK: "Dr. Colin Marlow."
PRESTON: "The one and only."

DEREK: "Dr. Marlow, Derek Shepherd, neuro. I'm doing a sigal sinus bypass today if you'd like to observe."
COLIN: "Really, that's quite a procedure."
PRESTON: "It's a good trick, but if you're really interested to see what this hospital can do, I'm performing a arterial switch operation for TGA this afternoon."
COLIN: "If you gentlemen are trying to intimidate the competition, it's working."
DEREK: "Good."
COLIN: "I'll see both of you in surgeries."

PRESTON: "She's a motivated student. It's nothing to be ashamed of."
CRISTINA: "Thank you."
PRESTON: "A bit of a kiss-ass, but that's hard to control."
GEORGE: "Look, they're coming out."
PRESTON: "That's Colin Marlow."
ALEX: "Like the Marlow transplant?"
PRESTON: "Like the greatest thing in cardiothorastic surgery in a generation. Dr. Marlow. I'm Preston Burke. I'm a great admirer of your work, sir. Particularly the..."
COLIN: "Yes, thank you... Would you excuse me for just a second?"

PRESTON: "How you doin', Grey?"
MEREDITH: "Oh, I'm fine, sir, thank you."

PRESTON: "You know, some do come back from this."
CRISTINA: "You know what? I’m not a civilian. I know the science here. It’s drinking time."
PRESTON: "Not yet. You have a responsibility to Meredith."
CRISTINA: "No. Uh-uh. I don’t do this stuff. You should know. I don’t go to great lengths."
PRESTON: "Well, you were there for me."
CRISTINA: "After. After I knew you were going to make it. Hey, I’m not proud. Okay, I just... I can’t. I can’t go back there. I can’t. I can’t go back there and watch her."
PRESTON: "Listen to me. This is about you and the woman you call your person. And you do know the science here. And if she dies, and you're sitting here when that happens, I can’t see you coming back from that. Come and say goodbye to your friend."

PRESTON: "There’s no change. Thought you should know."
CRISTINA: "No kidding."

RICHARD: "That's Ellis Grey's little girl!"
PRESTON: "We're all on the same side here, Chief."

ADDISON: "I gotta tell you. This group of interns..."
PRESTON: "Emotional."
ADDISON: "Headstrong."
PRESTON: "Hot-headed, stubborn. They think they know everything. You can only give them so much rope before they hang themselves with it. They lose all rationality, they won't listen to reason."
ADDISON: "Jeez, Preston. Don't hold back."

PRESTON: "The Chief is working on her."
DEREK: "He threw me out."
PRESTON: "What do you need?"
DEREK: "I need you to go in there."

Grey's Anatomy Quotes

Amelia: I think I'm falling in love with Owen Hunt, and I'm really afraid that it's gonna destroy me.
Derek: It wouldn't be love if it didn't.

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.

Meredith