Relax Marge, if God lets the Jews have Sunday on a Saturday, he'll be cool with this.

Reverend Lovejoy: I have a friend, I mean, a friend of a friend...
Homer: (Very loudly) Sex problem, eh?

(to Helen) You put on the Michael Bolton CD, I'll put on my edible vestments!

Marge: Reverend Lovejoy, our marriage needs this bed!
Helen Lovejoy: Our marriage needs it more!
Rev. Lovejoy: Well, I am reminded of the story of wise King Solomon.
Homer: Pfft. You would be.

Helen Lovejoy: (to Homer) You are so blind, even Jesus couldn't heal you.
Reverend Lovejoy: Helen please, don't drop the J-bomb.

Ned Flanders: Reverend, would you like to try some of my devil's food cake?
Reverend Lovejoy: Is that really devil's food?
Ned Flanders: No, it's angel's food with chocolate on top.
Reverend Lovejoy: Mmm-hmmm, I thought so.

Helen Lovejoy: Oh, Tim, calm down, he's just your old roomate from Texas Christian.
Reverend Lovejoy: He's like the Pope of this thing!! It would be like Mary Kay, visiting you, when you sold her cosmetics. That is if you had, stuck with it.
Helen Lovejoy: You asked me to quit, because I was making more then you.

Marge everything is a sin. Have you ever sat down and read this thing? (holds up the bible) -Technically we're not allowed to go to the bathroom.

Helen Lovejoy: Heh, this won't take long. He's clearly guilty. We'll probably be home by dinner time.
Jasper: Good. I hear the dog from Frasier is going to ride the dolphin on SeaQuest.

Helen Lovejoy: That animal of yours is certainly bad-tempered.
Lisa: Yeah, well you'd be grumpy, too if you were taken out of your natural habitat and gawked at by a bunch of slack-jawed yokels.
Cletus: (Pointing at Lisa) Hey, Ma! Look at that pointed-haired-ed little girl! (Chuckles)

Ned: What do you think, Reverend?
Reverend Lovejoy: Once something has been approved by the government, it's no longer immoral.
Crowd: Yeah!
Mr. Burns: By building a casino, I could tighten my stranglehold on this dismal town!
Crowd: Yeah!
(Barney burps)
Crowd: Yeah!

Reverend Lovejoy: God has never given up on anyone
Ned: What about Sodom and Gomorrah?
Reverend Lovejoy: He lovingly destroyed them.

The Simpsons Quotes

Sir, I got carsick in your office.

Ralph

Homer: (Wearing glasses) The sum of the square roots of any two sides of an isosceles triangle is equal to the square root of the remaining side!
Man: (From inside a bathroom stall.) That's a right triangle, you idiot!
Homer: D'oh!