"Just shut up and count backwards already."

"Richard... you're a good friend." RICHARD

MIRANDA: "You are a surgical junkie. Go home!"
RICHARD: "Adele is already mad. I'm in trouble no matter what ... and there's a wipple happening in OR2."
MIRANDA: "Go home, right now!"
RICHARD: [walking away] "You know this kind of treatment is the reason they call you the Nazi!"
MIRANDA: [smiles] "Happy Thanksgiving."

MEREDITH: "We have... custody of a penis?"
RICHARD: "Yes. Until the cops come for it."
MEREDITH: "Okay, well, what am I supposed to do with the penis?"

MIRANDA: "I'm pregnant, you blind moron."
RICHARD: "You’re what?"
MIRANDA: My heart rate is 110, I’m burning 3,000 calories a day, my legs are swollen, I've got indigestion and gas. Did you know carrying a boy in your uterus means you burn 10 percent more calories than if you had a girl? Guess what I’m carrying. I tried for seven damn years and a month before my fellowship notifications the stick turns blue. Men. From the very beginning they just suck the life right out of you. I’m not leaving. I’m pregnant."

RICHARD: "People! I know who did this, so you might as well come clean. I know!"
GEORGE: "With all due respect, sir, if you knew you wouldn't be asking us."
IZZIE: "I did it."
MEREDITH: "You have your suspicions, but you don't actually know."
CRISTINA: "Not for sure."
GEORGE: "And you can't do anything to any of us without proof, sir."

[opens door, sees Derek] "There's never a good place to hide in this hospital."

ADDISON: "I guess that puts an end to the evening."
DEREK: "Yeah."
RICHARD: "I guess it does." [Addison and Richard leave]
FINN: [to Meredith] "I'll drive you home."
DEREK: "Meredith." [Meredith, Finn and Derek all look at each other, exchanging knowing glances]
FINN: "Meredith..."

CAMILLE: "Be kind to Brian. He loves me. I've been loved. And that’s something everyone should have once in their life. I've been loved. Thank you for the prom, Uncle Richard."
RICHARD: "You're welcome."

RICHARD: "I've known you for a long time. I know your mother and father. And I know, beyond a shadow of a doubt, that you did not cut those LVAT wires. Meredith, I need you to tell me who did it."
MEREDITH: "I've been going over this and over this in my mind trying to piece this together. It was you. You're the reason my parents broke up. And it wasn't just an affair, she really loved you. It wasn't just this cheap thing where she didn’t tell you she was married. It wasn't all a lie. She left her husband for you. But you stayed with your wife, because it was the right thing to do. Maybe safe, but she was the right person for you to be with. Let's face it, my mother? Nothing wrong with being safe, being with the good guy because he's good and we are talking about forever here. You've never regretted your decision. You've never looked back... right?"

IZZIE: "I'm a pretty girl."
RICHARD: "What?"
IZZIE: "I'm not being arrogant, it's just, it's just kind of a fact. For a long time I made a career from my looks, so I get it, I'm a pretty girl. And not in a 'from a certain angle' way, in an obvious way. It’s the blonde thing and the big boobs thing. Big boobs are a key to 'obvious pretty' if you know what I'm saying."
RICHARD: "Dr. Stevens-"
IZZIE: "It's how men see me. I'm not a smart girl or an interesting girl, I'm a pretty girl. The blonde and the boobs, it confuses guys into thinking I'm someone else. And I'm used to it. And I'm used to them walking away when they realize… But then Denny goes and asks me to marry him."
RICHARD: "Is that why you cut the wires?"
IZZIE: "He doesn't make me feel like I'm a pretty girl. He makes me feel like… like me. I think he might know me. And so, if I did cut the LVAT wire, and I'm not saying that I did, but if I did, then no. I don't feel guilty. I know that I should. I would if it were anybody else's. But I can't feel anything but happy."

CRISTINA: "How do you keep your edge, sir? Because I've watched you and you've been doing this a long time and you're clean, you're focused, you are the job. Nothing gets to you. And the thing is sir, I was like that, until I got here. Until I actually started doing this job and now everything is... is fuzzy and-"
RICHARD: "That’s beside the point."
CRISTINA: "No, you see sir, this is the point. Because I can't tell you. I can't tell you what happened in that room. And before, I could have. No guilt, no loyalties, no problem. Before, before I wouldn't have even been in that room. I wouldn't have gotten involved. I would have never frozen in surgery. I would have told him what I thought he should do. I had an edge sir. I had an edge and I've lost it, and I need it. I need it back. So, if you could just tell me, how you keep yours and how not to be affected, I know I could be a great surgeon. So if you could just give me the answers, I would really appreciate it."
RICHARD: "You're excused, Dr. Yang."
CRISTINA: "But-"
RICHARD: "You're excused. Go."
CRISTINA: "I'll tell you, I'll tell you who cut the LVAT wires if you'll please-"
RICHARD: "No you won't, I don't wanna know. Not from you. Yeah, I have the answers, but I can't tell them to you. I'm not going to be responsible for you becoming less human."

[the cast, narrating]
MEREDITH: "Human beings need a lot of things to feel alive."
GEORGE: "Family"
CRISTINA: "Love"
IZZIE: "Sex"
DEREK: "But we only need one thing"
RICHARD: "To actually be alive."
CRISTINA: "We need a beating heart."
ADDISON: "When our heart is threatened"
ALEX: "We respond in one of two ways."
GEORGE: "We either run or-"
IZZIE: "We attack."
RICHARD: "There's a scientific term for this."
ALEX: "Fight..."
ADDISON: "...or flight."
MIRANDA: "It's instinct."
MEREDITH: "We can't control it."
IZZIE: "Or can we?"

Grey's Anatomy Quotes

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.

Meredith

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)