[drinking coffee] "You don't know how much I wish this was bourbon."

ADDISON: "I know what you're going to say Richard, but if you knew the day I've had-"
RICHARD: "Everybody in this hospital has those days, Addison, and no one makes a scene in front of their peers. Get it together. [pauses] Addison?"
ADDISON: "I can't compete. He's not having an affair. He's not trying to hurt me. He's just... the only people who don't know that Derek loves Meredith are Derek and Meredith. How do I compete with that?"

DEREK: "Maybe you should've thought of all this before you gave chief to Burke and invited Satan to Seattle."
RICHARD: "Satan?"
ADDISON: "Good morning Richard, like the hat."
DEREK: "Satan speaks."
ADDISON: "Actually, I prefer to be called ruler of all that is evil. But I will answer to Satan."

"I've been sitting home for a week watching Oprah give away things on T.V. Oprah, Derek!"

RICHARD: "You called my wife?"
DEREK: "You called mine!"

ADDISON: "Am I interrupting?"
RICHARD: "You're never interrupting."
DEREK: "She's always interrupting."

RICHARD: "You and I both know she's the best in the field. Bringing Addison out was a business decision. It's nothing personal."
DEREK: "Oh, well, that's a relief. Not personal. It's personal to me!"

NURSE: "Chief, Adele just called."
RICHARD: "Please tell her I'm in-"
NURSE: "She knows you're not in surgery and she said to tell you, quote, we're going to our niece's school pageant this morning. You've known about it for months, and after what you pulled on Thanksgiving... then she started using a great many words that I don't feel comfortable repeating."
RICHARD: [sighs] "Look, I have seven surgeons on vacation."
NURSE: "There was something in there about divorce."

RICHARD: [looking at the board] "Anxiety attacks, aneurysms, and ulcers."
MIRANDA: "Must be December."

RICHARD: "So don't move here for Derek. Move for you."
ADDISON: "Excuse me?"
RICHARD: "With your practice based here, and the money I'll put into promoting you, you'll be one of the biggest names outside Manhattan."
ADDISON: "You're serious?"
RICHARD: "I'm ready to put my money where my mouth is."

PRESTON: "I don't want preferential treatment."
RICHARD: "And you're not gonna get it. You're not married, you're not hiding. You came to me. You clearly value your relationship. What you two have together, I understand that, Preston, and it does matter."

THATCHER: "I spent years looking at this board. Holding a crying baby, trying to get an idea of when my wife would get out of surgery. 'Appy,' that takes about an hour. Now anything with the word "cardio" in it, I knew not to plan on seeing her that day."
RICHARD: "Thatcher, are you aware of what's going on with Ellis?"
THATCHER: "You have no right. No right... to talk to me about Ellis."
RICHARD: "I'm sorry. I... I was trying to talk to you about Meredith. Thatcher, Ellis has Early Onset Alzheimer's. It's advanced. It's hard on Meredith as you can imagine, and I thought you'd want to know."

Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

I want to marry you. I want to have kids with you. I want to build us a house. I want to settle down and grow old with you. I want to die when I'm 110 years old, in your arms. I don't want 48 uninterrupted hours. I want a lifetime. Mmm. Do you see what happens? I say things like that and you fight the urge to run in the opposite direction. It's okay, I understand. I didn't, but now I do, I do. You're just getting started and I've been doing this for a long time now. Deep down, you're still an intern, and you're not ready.

Derek