CRISTINA: "How do you keep your edge, sir? Because I've watched you and you've been doing this a long time and you're clean, you're focused, you are the job. Nothing gets to you. And the thing is sir, I was like that, until I got here. Until I actually started doing this job and now everything is... is fuzzy and-"
RICHARD: "That’s beside the point."
CRISTINA: "No, you see sir, this is the point. Because I can't tell you. I can't tell you what happened in that room. And before, I could have. No guilt, no loyalties, no problem. Before, before I wouldn't have even been in that room. I wouldn't have gotten involved. I would have never frozen in surgery. I would have told him what I thought he should do. I had an edge sir. I had an edge and I've lost it, and I need it. I need it back. So, if you could just tell me, how you keep yours and how not to be affected, I know I could be a great surgeon. So if you could just give me the answers, I would really appreciate it."
RICHARD: "You're excused, Dr. Yang."
CRISTINA: "But-"
RICHARD: "You're excused. Go."
CRISTINA: "I'll tell you, I'll tell you who cut the LVAT wires if you'll please-"
RICHARD: "No you won't, I don't wanna know. Not from you. Yeah, I have the answers, but I can't tell them to you. I'm not going to be responsible for you becoming less human."

[the cast, narrating]
MEREDITH: "Human beings need a lot of things to feel alive."
GEORGE: "Family"
CRISTINA: "Love"
IZZIE: "Sex"
DEREK: "But we only need one thing"
RICHARD: "To actually be alive."
CRISTINA: "We need a beating heart."
ADDISON: "When our heart is threatened"
ALEX: "We respond in one of two ways."
GEORGE: "We either run or-"
IZZIE: "We attack."
RICHARD: "There's a scientific term for this."
ALEX: "Fight..."
ADDISON: "...or flight."
MIRANDA: "It's instinct."
MEREDITH: "We can't control it."
IZZIE: "Or can we?"

RICHARD: "I know your type. You're a surgical junkie."
CRISTINA: "Sir?"
RICHARD: "I'm just saying, it's not going to be easy for you to be away from the O.R. for long."
CRISTINA: "No sir."
RICHARD: "And if you want to get back to the O.R., you're gonna tell me what I need to know."
CRISTINA: [pauses] "You're right, it's not easy for me to be away from the O.R. And it's not easy for me to sit in front of you, or any other authority figure for that matter, and not be able to give you the exact answer that you want to hear. I'm the one with the answers. I've always been the one with the answers. But right now, sir, I don't have any."

RICHARD: "One of you compromised a patient's life. One of you stole an organ. One of you jeopardized the integrity of this hospital and of UNOS. Now you tell me and you tell me right now. [silence] Alright, fine. No surgeries."
CRISTINA: "Sir?"
RICHARD: "No one scrubs in, no one watches from the gallery, no one so much as goes near the O.R. Until someone confesses, you will share a single patient, Camille Travis. Whatever she wants, the five of you will provide it. Get the hell out of my sight."

RICHARD: "Yang, Shepherd's asking for you."
CRISTINA: [pauses] "For Burke's surgery?"
RICHARD: "Yes, hurry up."
CRISTINA: "Uh... I can't. I'm in a time-out.
RICHARD: "Well, time-out's over, Yang. We need you."

[drinking coffee] "You don't know how much I wish this was bourbon."

ADDISON: "I know what you're going to say Richard, but if you knew the day I've had-"
RICHARD: "Everybody in this hospital has those days, Addison, and no one makes a scene in front of their peers. Get it together. [pauses] Addison?"
ADDISON: "I can't compete. He's not having an affair. He's not trying to hurt me. He's just... the only people who don't know that Derek loves Meredith are Derek and Meredith. How do I compete with that?"

DEREK: "Maybe you should've thought of all this before you gave chief to Burke and invited Satan to Seattle."
RICHARD: "Satan?"
ADDISON: "Good morning Richard, like the hat."
DEREK: "Satan speaks."
ADDISON: "Actually, I prefer to be called ruler of all that is evil. But I will answer to Satan."

"I've been sitting home for a week watching Oprah give away things on T.V. Oprah, Derek!"

RICHARD: "You called my wife?"
DEREK: "You called mine!"

ADDISON: "Am I interrupting?"
RICHARD: "You're never interrupting."
DEREK: "She's always interrupting."

RICHARD: "You and I both know she's the best in the field. Bringing Addison out was a business decision. It's nothing personal."
DEREK: "Oh, well, that's a relief. Not personal. It's personal to me!"

Grey's Anatomy Quotes

There's a reason I said I'd be happy alone. It wasn't 'cause I thought I'd be happy alone. It was because I thought if I loved someone and then it fell apart, I might not make it. It's easier to be alone, because what if you learn that you need love and you don't have it? What if you like it and lean on it? What if you shape your life around it and then it falls apart? Can you even survive that kind of pain? Losing love is like organ damage. It's like dying. The only difference is death ends. This? It could go on forever.

Meredith

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)