Sheldon: Do you know where the phrase jibber jabber comes from?
Penny: Oh my god, you're about to jibber jabber about "jibber jabber?"

Leonard: Beekeeper to King 12. I capture your pope and release the swarm. Checkmate on Sheldon.
Sheldon: I knew I should've given my pope the jet pack.

My recommendation is that you gobble these up like Tic Tacs.

You may have gone to Cambridge, but I'm an honorary graduate of Starfleet Academy.

... with the whiter-than-Marshmallow-Fluff Leonard Hofstadter.

I understand the alcohol has stirred up whatever it is that makes girls go wild ... but I really need to talk to smart Amy right now.

Irrelevant. Leonard doesn't trim his nose hair. He thinks because he's short, no one can see up there.

Everyone was set a-twitter. Although oddly, no one tweeted.

Amy: The meme has reached full penetration.
Sheldon: Pun intended?
Amy: No. Happy accident.

Amy: I should let you know that she asked for details about our dalliance.
Sheldon: Interesting. So it went beyond the mere fact of coitus to a "blow by blow" as it were.
Amy: Pun intended?
Sheldon: I'm sorry. What pun?

Three thousand hours, three thousand hours clicking on that mouse, collecting weapons and gold. It's almost as if it was a huge waste of time.

Leonard: You called the police because someone hacked your World of Warcraft account?
Sheldon: What choice did I have? The mighty Sheldor, level 85 blood elf, hero of the Eastern kingdoms has been picked clean, like a carcass in the desert sun. Plus, the FBI hung up on me.

TBBT Quotes

Oh, Bernadette, please play my clarinet.

Raj's poem

Sheldon: I'll have a diet Coke.
Penny: Can you please order a cocktail? I need to practice mixing drinks.
Sheldon: Fine... I'll have a virgin Cuba Libre.
Penny: That's... rum and Coke without the rum.
Sheldon: Yes, and would you make it diet?