Howard, you know me to be a very smart man. Don't you think that if I were wrong, I'd know it?

Penny: You know, I do understand what you're going through.
Sheldon: Really? Did you just have the Nobel Prize in Waitressing stolen from you?

Hello, Penny. I realize that you're currently at the mercy of your primitive biological urges, but as you have an entire lifetime of poor decisions ahead of you, may I interrupt this one

Sheldon: It must be an emergency; everyone at the university knows that I eat my breakfast at 8 and move my bowels at 8:20
Leonard: Yes, how did we live before Twitter?

Sheldon: Why does Leonard get to go?
Wolowitz: Because he's upset over his situation with Penny, and if I have to hear about it again, I'm gonna kick him in his ovaries

I have to say I thought the toilet humor would get less funny with repetition. Apparently there is no law of diminished comedic returns when it comes to space poop

Sheldon: You have to check your messages, Leonard! Leaving a message is one-half of a social contract, which is completed by the checking of the message. If that contract breaks down, then all social contracts break down and we descend into anarchy.
Leonard: It must be hell inside your head.
Sheldon: At times.

Stuart: Here Sheldon. I pulled the new Hellboy for you. It's mind-blowing.
Sheldon: Excuse me! Spoiler alert!
Stuart: What? I didn't spoil anything.
Sheldon: You told me it's mind-blowing, so my mind is going into it pre-blown. Once a mind is pre-blown, it cannot be re-blown.
Stuart: I'm sorry.
Sheldon: Said the Grinch to Christmas.

Leonard: What were you doing at Penny's?
Sheldon: Well, we had dinner, played some games, and then I spent the night. Oh, and you'll be happy to know that I now have a much better understanding of "friends with benefits"

You know, I'm given to understand that there's an entire city in Nevada devoted specifically to help people like Howard forget their problems. They replace them with new problems such as alcoholism, gambling addiction and sexually transmitted diseases

What exactly does that expression mean, "friends with benefits?" Does he provide her with health insurance?

You're probably thinking, "the comic book store, on a Thursday? Why I've fallen down the rabbit hole and into a land of madness." What you have failed to take into account, Penny, is that this is "Anything Can Happen Thursday"

TBBT Quotes

Mrs. Cooper: Shelly! I'm so glad you're here!
Sheldon: I saw you having naked sex.

You can't ruin a friendship with sex that's like trying to ruin ice cream with chocolate sprinkles.

Raj