Leonard: So a few things don't go your way and your best decision is to ride the rails like a hobo?
Sheldon: I suppose it is. Except I have a credit card. And I refuse to carry my laptop at the end of a stick. And I'd sooner die than eat beans out of a can.

I do not accept this. Everything is changing and I hate it. It stops now.

Amy: Maybe you'll love living alone.
Sheldon: I don't know. Perhaps.
Amy: And if it turns out you don't ... you and I could live together.
Sheldon: You and... Oh, sure. And while we're at it, why don't we get engaged, too? Why don't we get a little house, start a family? Enjoy our sunset years together? Do you hear yourself, woman?!
Amy: Sheldon, it was just a thought.
Sheldon: No. Here's a thought. You're not moving in, Leonard's not moving out, everything stays exactly the way it is.

Sheldon: Move across the hall?! Did you take a marijuana?!
Leonard: No, I did not.
Sheldon: Did you get hit on the head with a coconut?
Leonard: No.
Sheldon: Well, then, I'm all out of guesses.

Sheldon: She's spent many nights here, and you're worried about preserving the myth of her virginity before the wedding.
Leonard: I'm not.
Sheldon: Good, because not only has that ship sailed, if it hit an iceberg, countless men would perish.

Sheldon: I don't have all the ingredients to make chai tea.
Raj: You don't have to make me anything.
Sheldon: No, I do. You're upset about Emily and you're Indian. I need to make you chai tea. Now, I have all the ingredients except cardamom seeds. Do you happen to have any on you?
Raj: Sorry, I left them in my turban.
Sheldon: Oh, I'll make English breakfast tea. They destroyed your culture. That's close enough.

Raj: Aren't you gonna get 3-D glasses?
Sheldon: I brought my own. No sense in risking bridge-of-nose herpes.
Raj: Is that a real thing?
Sheldon: Well, until they invent nose condoms, I'm not finding out.

Penny: There's no reason why I shouldn't be the best bisexual go-go dancer slowly transforming into a killer gorilla
anyone's ever seen.
Leonard: I don't know. The bisexual gorilla go-go dancer in Schindler's List is tough to beat.
Sheldon: Ah, very good. Because a gorilla go-go dancer
of any sexual preference would be out of place in a film about the Holocaust.
Leonard: It only gets funnier when you explain it, Sheldon.
Sheldon: I know.

Sheldon: But I do appreciate them.
Arthur: Well, then, what am I doing in the swamp dressed like Friar Tuck? Appreciate them, Sheldon.

All the men I've looked up to have gone away.

I've already had to say goodbye to 11 Doctor Whos.

Arthur: Most-most of my robes open ... in the back.
Sheldon:Those are your Jedi robes.
Arthur: What is this?
Sheldon: Oh! Be careful with that.
Arthur: Whoa! Oh, neato. [laughs] I'm-I'm gonna need a Band-Aid.

TBBT Quotes

Sheldon: Is anyone else troubled by the Spider-Man theme song?
Leonard: Why would it trouble you? It's like your third favorite cartoon theme song.
Sheldon: It is, right behind [Sheldon sings "Inspector Gadget" and "Teenage Mutant Ninja Turtles" theme songs]
Sheldon: However, the Spider-Man lyrics posit that Spider-Man's Spider-Man does whatever a spider can.
Howard: Yeah, so?
Sheldon: I can think of many things that Spider-Man can't do that a spider can. One crawl in your ear and die, two legally leave Guatemala without a passport, and three have sex with a spider.

I was expecting applause but I suppose stunned silence is equally appropriate.

Sheldon