I knew my play was good, just like I knew your play was a mediocre patchwork of hackneyed ideas and tired cliches! You have no idea how hard it was to sit in that theater with those braying hyenas! Couldn't you tell something was up when Chris and the fat man could follow the plot?!

Lois: Remember kids, if it's terrible, at the end we all say "You did it!"
Stewie: I can't believe we're going to the theater the same day Chris drowned a mouse in a puddle. I mean, don't we need a day to clear our heads?

Brian: I think, I think we're launching!
Lois: Oh my god, everyone strap yourselves in! Stewie, hold my hand.
Stewie: No thanks, I prefer to die giving you the finger.
Peter: If this is what it takes to get out of Florida, fine.

Oh by the way, there's a baby in my preschool with HIV, and my teacher gave you something to sign to get him kicked out.

Meg: I can only imaging what it was like for them on that very first Christmas.
Brian: Yeah, it was probably very moving. And fictional.
Stewie: Jesus lived with us for like a week, what else do you need?

No matter how low I turn the volume, Aziz Ansari is always shouting at me. What did I do?

Brian: Alright, very funny, Stewie. You replaced my Jack Daniel's with flat Diet Coke.
Stewie: No I didn't! And you're noticing this at 8:20 in the morning? What has happened to your life? Do you need to talk?

Stewie: No, that's great, actually because, now anyone walking behind you will know you had 60 dollars.
Peter: Whoa, that is awesome, Lois! Your bum looks like an NBA star's arm! Except it's not paying someone to install a Playstation in a car.

Lois: You guys shouldn't have done this!
Stewie: Hey, any time you can celebrate the end of someone's periods.

Nice throw, Casey Anthony.

Stewie: Ah, look at this, she's taped photographs of Virginia Woolf and Katy Perry on the inside cover, as if she's some sort of hip hybrid of those two things.
Brian: Yeah, like she could ever write "Who's Afraid of Virginia Woolf?"
Stewie: "Who's Afraid of Virginia Woolf" was not written by Virginia Woolf.
Brian: Yeah, obviously, but y'know, it's pretty much about her.
Stewie: It really isn't, Brian.

Meg: Oh, he's so cute!
Stewie: Oh my god, we're getting closer to the beginning! You're Lacey Chabert!

Family Guy Quotes

Stewie: (Comes into the bedroom) Lois! Lois! Lois! Lois! Lois! Lois! Mom! Mom! Mom! Mommy! Mommy! Mommy! Mama! Mama! Mama! Ma! Ma! Ma! Ma! Mum! Mum! Mum! Mum! Mummy! Mummy! Mumma! Mumma! Mumma!
Lois: What!?
Stewie: Hi! (Giggling and running out of the room)

Bill Clinton: All right, are you ready for another round of N.A.F.T.A
Lois Griffin: What does N.A.F.T.A. mean?
Bill Clinton: 'Nother Afternoon of F****** That Ass!