Simmons: This is the victim's brain.
Coulson: It looks like a burnt baked potato.

I’m tired of secrets. So I’m glad we’re here, I need to root out all the secrets.

Coulson

Coulson: Alright what’s up?
May: You tell me?
Coulson: You’re talking, more than ever.

Ward: It’s strategic.
Simmons: It’s adorable.
Skye: The Tin Man has a heart after all.

Skye: Wow, look at them, the popular kids. Who knew?
Ward: I did.

I even let them tag me like a stray dog.

Skye

Coulson: We'll be making the calls, picking the ops, no red tape. [looks around] This is where they actually make the red tape isn't it?
May: You're really just asking me to drive the bus?
Coulson: No. [smiles] It's a really nice bus.

Skye: Are you Ok? I heard what you were saying back there.
Coulson: It wasn't real. They were just messing with my head.

Dr. Garner: I haven't worked with S.H.I.E.L.D. in a long while. I moved on for a reason.
May: It's a different S.H.I.E.L.D., Coulson's the director now.
Dr. Garner: Okay, but why me? Is this Skye that bad?
May: She's that good; good agent.

Coulson: I heard what you did for me. I think it’s time that we remove this. [speaks to bracelet] Disengage bracelet.
Skye: Are you kidding me?
Coulson: I though you like that.

My entire life I've been searching for my parents, and my search ended with answers that are so much worse than I could have imagined.

Skye

Coulson: You agree with her. You think Skye is more than we can handle.
Agent May: Look, most of the time, I believe what I see, you know that but...
Coulson: But?
Agent May: You died. You were brought back, with a map to a city encoded in your DNA. Our team's first mission.
Coulson: We picked up Skye.
Agent May: Last week, we took her to that city. I can't help but remember what Lumley said. Wherever Skye goes...
Coulson: Death follows.

Agents of S.H.I.E.L.D. Quotes

Kasius: Yo-Yo Rodriguez? How peculiar.
Yo-Yo: Says the space mime!

Sousa: Hey, what are you doing up?
Daisy: Why do you care?
Sousa: Because you don't.