Harlan: You were my friend.
Sherlock: I was your employer, Harlan. And you were my consultant. One of many.
Harlan: I know that I am a little obsessed with what I do. That has always made it hard to make friends. And I used to feel pretty bad about that and then I meet you. And I thought to myself, hey, if it doesn't bother him, why should I let it bother me? I got a lot out of the work we did. A lot. But if someone like you, thinks I'm a loser, then ...

In the wrong hands, math can be manipulated, abused. I decided to do something about it. You catch people who murder other people. I catch people who murder math.

Harlan

Sherlock: Your home, Watson, is utterly pleasant.
Joan: You say that like it's a bad thing.
Sherlock: When you told me you wanted a life of your own, I didn't realize you meant you wanted the same life everyone else has ... anyway, it's none of my business.

Watson seems adequately sexed.

Sherlock

It's just something that happened. It's in the past now. Let's just leave it there, shall we?

Kitty

She's strong, Watson. Smart. The training I'm attempting to provide her, the same training I provided you, for her has an ulterior motive. It is, in part, an attempt to channel residual feelings that she has into a productive skill. I believe she will make an excellent investigator. Just not today.

Holmes

So let's say I am being framed, if that were true, I'd take that fall. I know it wouldn't get Amy back, but at least she would know that I'm the one who got the guy.

Coleman

Holmes: It's unlikely I'll find another case half as worthy of my attention.
Watson: I could say the same thing.
Holmes: And indeed you should.

Watson: You work for Sherlock?
Kitty: I don't work for anyone. I'm his new partner.

Watson: Why are you here?
Sherlock: Isn't it obvious? I belong here. As do you.

In the event I failed, it would not be in front of you.

Sherlock

But you were right. I don't need you anymore. Still don't.

Watson

Elementary Quotes

Ben Garrett: How do you do all that?
Sherlock: I was bitten by a radioactive detective.

Holmes: Why do you suppose you hate your job so much?
Watson: I don't hate my job.
Holmes: You have two alarm clocks. No one with two alarm clocks loves their job. Two alarm clocks mean it's a chore for you to get up in the morning.