[To Joan] I'm curious to know which one of us is right about my brother. I have my money on me.Sherlock
Sherlock is addicted to being himself.Mycroft
Sherlock: Watson, this is Fatty.
Mycroft: Fatty? Not anymore.
Sherlock: Lap band?
Sherlock: Exercise requires energy and ambition, and you've never had either.
What do you expect from a guy named Geezer Bob?Joan
Hopkins: You look exactly the same!
Sherlock: As do you. Except that you've gained a stone and quarter, and your hairline is receding.
Hopkins: You're slipping, I've gained exactly a stone and a half.
Sherlock: I'm not slipping, I've just grown more courteous.
[To Joan] Without you the airline might seat me next to a morbidly obese person, or child, or morbidly obese child.Sherlock
I see you've been tending to your self defense.Sherlock
[To Moriarty] We both made a mistake. We fell in love.Sherlock
Joan: You're scared of him.
Moriarty: I'm scared of what he might make me do.
[To Moriarty] You said there is only one person who surprises you. I guess they're are two.Sherlock
[To Moriarty] She solved you, you know. My mascot.Sherlock
You named a bee after me?Watson