Sometimes the future changes quickly and completely, and we’re left with only the choice of what to do next. We can choose to be afraid of it, to stand there trembling not moving, assuming the worst that can happen or we step forward into the unknown and assume it will be brilliant.

Cristina

Don't wonder why people go crazy. Wonder why they don't. In face of what we can lose in a day, in an instant, wonder what the hell it is that make us hold it together.

Meredith

Owen: It's a cute baby, right?
Cristina: Its small features and oversized thighs trigger a hormonal response from humans. It's autonomic. It's what keeps us from eating them.

[narrating] "Maybe we're not supposed to be happy. Maybe gratitude has nothing to do with joy. Maybe being grateful means recognizing what you have for what it is. Appreciating small victories. Admiring the struggle it takes simply to be human. Maybe we're thankful for the familiar things we know. And maybe we're thankful for the things we'll never know. At the end of the day, the fact that we have the courage to still be standing is reason enough to celebrate."

MEREDITH

I don't have to say a word. She just looks at me and sees who I am and how I feel and accepts it. She doesn't try to change it or wants to change it. That person. There's a billion people but I imagine there's only one of her.

Owen

Just when we think we figured things out, the universe throws us a curveball. So, we have to improvise. We find happiness in unexpected places. We find ourselves back to the things that matter the most. The universe is funny that way. Sometimes it just has a way of making sure we wind up exactly where we belong.

Meredith

We’ll try again and we’ll fail again because that’s what progress looks like. Progress looks like a bunch of failures. And you’re going to have feelings about that because it’s sad, but you cannot fall apart. And then one day, we will succeed and save a person’s life and we will walk on the moon.

Meredith

They say the inability to accept loss is a form of insanity, it's probably true. But sometimes, it's the only way to stay alive.

Meredith

[narrating] "A wise man once said you can have anything in life if you will sacrifice everything else for it. What he meant is nothing comes without a price. So before you go into battle, you better decide how much you're willing to lose. Too often, going after what feels good means letting go of what you know is right, and letting someone in means abandoning the walls you've spent a lifetime building. Of course, the toughest sacrifices are the ones we don't see coming, when we don't have time to come up with a strategy to pick a side or to measure the potential loss. When that happens, when the battle chooses us and not the other way around, that's when the sacrifice can turn out to be more than we can bear."

MEREDITH

You are my person. You will always be my person.

Cristina

[in flashback]
Meredith: I have no story. I'm just a girl in a bar.
Derek: I'm just a guy in a bar.

Lexie: You have to stop. You gotta stop talking to me and checking on me and talking to my boyfriend. I love you, and I'm always gonna love you, but I don't want to love you. I want to be happy, and Jackson makes me happy. And if you keep pulling at me, I'll come back to you.
Mark: You're right, I'm sorry.
Lexie: You got what you wanted you wanted a family so please just let me have what I wanted.
Mark: I said you're right. I told Avery I was letting you go. Did he tell you that part?
Lexie: Yes, it's paternalistic and weird.
Mark: I'm letting you go, Lexie. That means you've got to walk away.

Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."