Meredith: We're not 25, sleeping our way through Europe anymore.
Sadie: We could though. Think about it. We could get on a plane tonight, we could...
Meredith: No. NO! I can't. I have to work. I can't just...
Sadie: Wow... You know they've sucked the life right out of you. The Meredith I used to know...
Meredith: Is right here. I'm here. I just don't wanna sleep my way through Europe anymore. I wanna be here. I wanna be here!

Meredith: What happened?
Sadie: I quit. O'malley's a little narc. I'd rather be deemed a quitter than a cheater.
Meredith: Did you cheat your way into the program?
Sadie: I said I'm not book smart. You know that. I learn on my feet. I thought if I came to where you were, we... you could...
Meredith: Pull you through?
Sadie: We've seen each other through a lot.

Meredith: What's wrong with her?
Cristina: Well, she calls her Dad "Daddy."
Meredith: No. What's wrong with her? Why is she in the hospital?
Cristina: Oh, she isn't. Daddy is.
Meredith: Hey, you know you should ask Owen if he plays the guitar.

Meredith: I didn't even know Addison had a brother. I mean, you'd think Derek would have said something at some point. Or sang something, while he played his guitar.
Cristina: Speak English.
Meredith: Well, Derek used to play the guitar.
Cristina: Oh. Owen's ex fiance is in the hospital. Mmm... his ex-fiance he never told me about.

Meredith: You know Addison's brother probably isn't going to make it. His cysts are inoperable.
Cristina: Worms in the brain. Not how you wanna go.

Sam: I met, uh, Meredith.
Derek: Uh huh. She's not a midlife crisis. She's the real thing.
Sam: That's great. I'm happy for you man. I'm happy for you.
Derek: Yep. I should have called.
Sam: No...
Derek: I should have stayed in touch. It's my fault.
Sam: Hey, people move, they change. You know, we all do.

Sam: Your wife's in the chapel praying.
Derek: She's not my wife, and she doesn't pray.
Sam: Hey.
Derek: How are ya?
Sam: You know, mid life crisis. I got an earring... I got an earring, but I let the hole close up the very next day.
Derek: That would've... Would've been a very good look on you.

Meredith: He had all these friends. They sang, and they played guitar. It's almost like he was a totally different person.
Cristina: Well he was.
Meredith: It kinda freaks me out a little bit. I feel like I don't know him.
Cristina: Well, I don't know Owen. We don't. We don't know them.

Addison: Okay. I need to be distracted. Someone talk about something other than what's going on with my brother right now.
Callie: Er, Mark is good at talking about himself.

I call her, alright. I call my mother, once a week. I haven't told her I'm back, she thinks I'm calling from ... I keep the conversation short because I can't bear for her to know that the son she sent off to war is gone. He's gone. And if I just got in my car and drove the six miles to see her, she'd be so ... sad. And she would look at me in the same way Beth does, now. Like I'm not there. The only time I don't feel like a ghost is when you look at me, because when you look at me, you see me. You see me. This is me. This is me. Please, Cristina, see me. See me.

Owen (to Cristina)

Mark: Dr. Grey. It would appear that congratulations are in order.
Lexie: Thank you, Dr. Sloan.
Mark: And I'd also like it acknowledged that I offer these congratulations, professionally and respectfully, without any innuendo or inappropriate body language.
Lexie: Acknowledged, Dr. Sloan.

Callie (praying in chapel): Dear God, I need your guidance. I kissed a peds surgeon.
Addison: You kissed a peds surgeon?
Callie (still praying): I never thought I'd end up with a woman, God, I mean not until lately, but that's not the problem. The problem is the ped thing. She's perky and has butterflies on her scrub cap, but she's also hot. Really hot. So, help me get over the butterflies. Amen.

Grey's Anatomy Season 5 Episode 15 Quotes

Lexie: Wait, what's the prize?
Chief: You get to scrub in on Shepherd's craniotomy.
Lexie: Yeah!
Chief: And hold the doomsday sucker.
Lexie: What's the doomsday sucker?
Izzie: Doomsday sucker?
Chief: It's just a really big sucker.
Lexie: Yeah!

Every patient's story starts the same way. It starts with them being fine, it starts in the before. They cling to this moment, this memory of being fine, this before, as though talking about it may somehow bring it back. But what they don't realize is that they're talking about it to us, their doctors and that means there's no going back. By the time they see us, they're already in the after. And while every patient's story starts the same way, how the story ends depends on us, on how well we diagnose and treat. We know the story hinges on us and we all want to be the hero.

Meredith (narrating)