DEREK: "Hey."
MEREDITH: "Hey! You okay? You seem ..."
DEREK: "Yeah. You know... holidays."
MEREDITH: "Oh. Yeah. I do know."

"Glad to know you can keep a secret, Grey."

ALEX

GEORGE: "Paging Dr. Karev-ian!" [laughs]
MIRANDA: "What did you just say?"
GEORGE: "Um, it, it's a joke, Kevorkian, Karev-ian... Alex Karev?"
MIRANDA: "I get the joke. I just don't think it's funny. You see this O'Malley? I make one mistake with this scalpel and this man's dead. My husband, he makes mistakes at his job all the time. As far as I know he's never killed anyone but I have. And YOU WILL. Alex did. He made a math mistake and a man died for it. Run that past your accountant. See how he'd feel if every mistake he made, someone ended up dead. You don't have to like Alex, you don't have to care about him, but you damn well have to be on his side."

[to Alex] "Enough with the ego, you big baby! I gave up a surgery for this! Now. Like I said, it hurts here, and here, and back here. Oh, and this morning? I noticed my poop was a funny grayish color."

MEREDITH

[narrating] "There's an old proverb that says you can't choose your family. You take what fate handa you. And like them or not, love them or not, understand them or not, you cope. Then there's the school of thought that says the family you're born into is simply a starting point. They feed you, clothe you, and take care of you until you're ready to go out into the world. There you find your own tribe."

MEREDITH

[to Justin] "I think you should decide to live. Live so you can become a doctor, and you can find a way to do heart transplants without someone having to die. Live so you can grow up and have kids and raise them not to believe in Santa. That would piss your mom off. Just decide to live. Because in your case, dying really isn't the best revenge."

CRISTINA

MIRANDA: "Do not kick me!"
GEORGE: "Excuse me?"
MIRANDA: "Are you kicking me under the table, O'Malley?"
GEORGE: "No..."
MIRANDA: "Than clearly I wasn't talking to you." [looks down at her stomach] "You cannot kick me when I am doing my job. Thank you."

MEREDITH: "We know he cheated on you. That's why we let you turn the house into Santa's Freaking Village. We're not big on holidays. We're trying to be supportive, because you're having a hard time. But right now, Alex is having a harder time."
IZZIE: "Why should anybody care what kind of time Alex is having!?"
MEREDITH: "Because he's Dirty Uncle Sal!"
IZZIE: [looks confused]
MEREDITH: "Dirty Uncle Sal. The one who embarrasses everyone at holidays and family reunions and who can't be left alone with the teenage girls, but you have to invite him anyway. Look... I have a mother who doesn't recognize me and as far as family goes, you guys are it. So I know you're pissed at Alex, but maybe... maybe you could try and help him anyway. Like, in the spirit of this holiday you keep shoving down everybody's throats."

GEORGE: [helping Alex practice] "Aw, my throat! It's like, wicked soar, yo. Plus I got, like, all deez sick breakouts!"
IZZIE: "You're helping him!?" [storms off]
GEORGE: [to Alex] "I was doing mono. The whole acne thing was just being a teenager."

"When you operate, the rest of the world goes away. No thirst, pain... but it's not that way when you're sharing your body with another person."

MIRANDA

CRISTINA: "I am a 55 year old man. I'm nauseous and I can't stop throwing up."
ALEX: "Forget it, alright. I didn't ask for anybody's help."
CRISTINA: "Look, evil spawn, you can nurse your pride -- the key word being nurse -- or you can pass your test and be a doctor. Up to you."
ALEX: [pauses] "Any abdominal pain?"
CRISTINA: "Yes, from my giant fat belly all the way to my back. Oh, and I'm drunk. Hiccup. Hiccup."

DEREK: "Do you happen to know what time of year neurosurgeons are busiest, Dr. Stevens?"
IZZIE: "There's a particular time of year?"
DEREK: "There's no hard or fast rule, but brain injuries tend to pile up around the holidays. Folks fall off roofs while they string up lights. They go skating for the first time in a decade and break their heads open. Every year people drive through blizzards to get to parties where they kiss germ infected strangers under poisonous mistletoe. Then they get drunk and smash their heads through their windshield on their way home. But there's no hard or fast rule."

Grey's Anatomy Season 2 Episode 12 Quotes

ADDISON: "Are you sad? Depressed? What? It's Christmas, Derek. We love Christmas. Or at least we used to."
DEREK: [pauses] "I'm not saying this to hurt you, or because I want to leave you, because I don't. Meredith wasn't a fling. She wasn't revenge. I fell in love with her. That doesn't go away because I decided to stay with you."

ALEX: "Why are you helping me after what I did?"
IZZIE: "'Cause it's what Jesus would freaking do!"