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[narrating] "Four hundred years ago, another English guy had an opinion on being alone. John Donne. He thought we were never alone. Of course it was fancier when he said it. No man is an island entire onto himself. Boil down that island talk and he just means that all anyone needs is someone to step in and let us know we're not alone. And who's to say that someone can't have four legs. Someone to play with, or run around with, or just hang out."

MEREDITH

MEREDITH: "You're still you?"
DEREK: "I'm still me."

GEORGE: "By the way, uh ... Sorry you had to see that little scene earlier."
PATIENT: "Oh, you mean the talk with the girl who isn't your girlfriend about the girl who you'd like to be your girlfriend?"
GEORGE: "Yeah."
PATIENT: "So is it true? Do you like this Meredith?"
GEORGE: [pauses] "I love her."
PATIENT: [smiles] "Sometimes, no matter how much you love someone, they just can't love you back in the same way. Believe me, son. Living with a woman who can't love you back? Way lonelier than being alone."

"When Derek broke up with you, nobody told you were better off without him. It's not supportive, it's condescending. I was there for you, and the one time I need you? Just go away, Meredith."

IZZIE

DEREK: "The first person I killed? I was a second-year resident. James Hanson. Go home, Dr. Karev. There's nothing you can do for him now."
ALEX: [pauses] "No one should die alone."

[to Alex] "Look, you screwed up. Mr. Martin's fried. He wakes up, you fried his brain. He dies, you killed him. Deal with it."

DEREK

IZZIE: "I'm telling you, Meredith was all over him."
CRISTINA: "Seriously, she was all over him? What, like mounting him, with all the babies watching? Seriously?"
IZZIE: "Well, she would have if I hadn't interrupted."
GEORGE: "She was talking to him."
IZZIE: "You don't talk to bastards who cheat on their girlfriends, George. That's the rule."
GEORGE: "You weren't officially his girlfriend."
IZZIE: "That's not the point."
GEORGE: "It is kind of the point. You don't see me getting all emotional over people I'm not dating."
IZZIE: "Really. You wanna go there?!"
GEORGE: [pauses] "No."
IZZIE: "I'm having a moment here. Don't mess with me!"
CRISTINA: "You're not going to have a nervous breakdown and kill yourself, are you?"
IZZIE: "No."
CRISTINA: "So, there's no chance you'll kill us?"
IZZIE: [storms off]
GEORGE: [tries to hide smile] "Okay, that was wrong on so many levels."
CRISTINA: "But it was good though?"
GEORGE: [laughs] "Yeah, it was."
CRISTINA: [laughs]

"You're not here to make friends, Addison. You're here to make better surgeons. Being a teacher can be a lonely business."

RICHARD

OLIVIA: "He dumped me for a girl he knows he can't have. Listen to me George. You, Meredith Grey? Never going to happen."
GEORGE: "Why, why, why would you even... why? Meredith?"
OLIVIA: [storms out]
GEORGE: [to patient] "She gave me syphilis."

[to George, Olivia] "You know what time it is? Time for you two kids to kiss and make up, that's what time it is!"

PATIENT

CONSTANCE: "He said he would leave me if I didn't help him. Things got out of control. He was gonna leave me. He was all I had."
CRISTINA: "Clearly being alone has its benefits."

"One day? Four razor blades and that's all you can give me? Come on, sugarplum, I thought we were having fun."

CONSTANCE
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Grey's Anatomy Season 2 Episode 11 Quotes

GEORGE: "She just smiled at me!"
IZZIE: "A, this is not a competition. And B? My quint kicks your quints' asses."

[narrating] "Forty years ago, the Beatles asked the world a question. They wanted to know where all the lonely people came from. My theory is that a great many of the lonely people come from hospitals. More precisely, the surgical wing of hospitals. As surgeons, we ignore our own needs so we can meet our patients' needs. We ignore our friends and families so we can save other people's friends and families. Which means that, at the end of the day, all we really have is ourselves. And nothing in this world can make you feel more alone than that."

MEREDITH
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