All my orgasms are gonna be self-made, hand crafted ones.

Maggie

Amelia: Owen and I are getting to know each other.
Meredith: How well? Pants on or pants off well? Is it just sex, or is there something more?

Amelia: I think I'm falling in love with Owen Hunt, and I'm really afraid that it's gonna destroy me.
Derek: It wouldn't be love if it didn't.

He's different. I don't know how to explain it, but I think he realizes what makes him happy and he's choosing it. And that makes me happy. I think this is his moment.

Meredith

Bailey: Grey, look I had to try.
Meredith: For your patient, I know, but now that's dozens of transplant patients that you just screwed out of a chance.

Jo: You need to expand your horizons.
Stephanie: My horizons haven't been expanded in a very long time.

Just because we can live without something, it doesn't mean we have to.

Meredith

Derek: I am calling post-it, Zola, Bailey, the tumors on the wall, ferryboat scrub caps. I thought D.C. was everything. I was wrong. You... you're everything. I love you and I'm not going to stop loving you. I can't live without you. I don't want to live without you, and I'm going to do everything in my power to prove it.
Meredith: I can live without you, but I don't want to. I don't ever want to.

You want to be a mess, be a mess. I don't care. I can take it.

Alex

Ben: I have a beautiful and very strong wife.
Stephanie: Ew, Warrren. No, I want your case.

Meredith: It seems like you came home because you thought you were in trouble.
Derek: I came home because we're on trouble. I came home to work on us. I came home.

There’s this thing I used to do when I was a kid to my mom’s VCR. I’d take it apart piece by piece, then put it back together again. But inevitably, there was always a piece or two left over. Something I didn’t quite know what to do with. So, what do you do with that piece? Do you try to fit it back in? Do you try to make it work? Or do you decide you can live without that missing piece?

Meredith

Grey's Anatomy Quotes

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.

Meredith

Doesn't matter how tough we are, trauma always leaves a scar. It follows us home, it changes our lives, trauma messes everybody up, but maybe that's the point. All the pain and the fear and the crap. Maybe going through all of that is what keeps us moving forward. It's what pushes us. Maybe we have to get a little messed up, before we can step up.

Alex (narrating)