Jo: You need to expand your horizons.
Stephanie: My horizons haven't been expanded in a very long time.

Just because we can live without something, it doesn't mean we have to.

Meredith

Derek: I am calling post-it, Zola, Bailey, the tumors on the wall, ferryboat scrub caps. I thought D.C. was everything. I was wrong. You... you're everything. I love you and I'm not going to stop loving you. I can't live without you. I don't want to live without you, and I'm going to do everything in my power to prove it.
Meredith: I can live without you, but I don't want to. I don't ever want to.

You want to be a mess, be a mess. I don't care. I can take it.

Alex

Ben: I have a beautiful and very strong wife.
Stephanie: Ew, Warrren. No, I want your case.

Meredith: It seems like you came home because you thought you were in trouble.
Derek: I came home because we're on trouble. I came home to work on us. I came home.

There’s this thing I used to do when I was a kid to my mom’s VCR. I’d take it apart piece by piece, then put it back together again. But inevitably, there was always a piece or two left over. Something I didn’t quite know what to do with. So, what do you do with that piece? Do you try to fit it back in? Do you try to make it work? Or do you decide you can live without that missing piece?

Meredith

Don't apologize for caring about your [Jo] patients. A lot of doctors aren't willing to go all in. It hurts too much. But that's what's going to make you such an excellent doctor.

Miranda

Callie: You [Meredith] and Derek are living proof that love exists. That it works, that there is hope. You guys are a freaking romance novel, and I, for one, am rooting for you two. Team MerDer!
Alex: I'm not saying that.

Meredith: He's done this before.
Maggie: What?
Meredith: Moved to a new city, got a new job, ignored his wife's calls, met a girl, fell in love, started over.
Callie: Wait, what are you talking about, "met a girl"?
Meredith: Me. He met me. He left Addison when the marriage got hard, moved to Seattle, met me in a bar. What if he's doing the same thing now?

You're [Callie] right. Godspeed. Go kiss everyone.

Arizona

Jackson: What is the matter?
April: What's the matter is that you keep holding me like this delicate flower that's gonna break every time you look at me. That is what is the matter.

Grey's Anatomy Quotes

The first time I kissed my wife, she wasn't my wife then, she was just this girl in a bar. But when we kissed, it was like, I gotta tell you, it was like I'd never kissed any other woman before. It was like my first kiss. The right kiss.

Derek

[narrating] "At some point, you have to make a decision. Boundaries don't keep other people out, they fence you in. Life is messy, that's how we're made. So you can waste your life drawing lines or you can live your life crossing them. But there are some lines that are way too dangerous to cross. Here's what I know. If you're willing to throw caution to the wind and take a chance, the view from the other side... is spectacular."

MEREDITH