[narrating] "Karma. One way or another it will leave us to face ourselves. We can look our karma in the eye or we can wait for it to sneak up from behind. But karma will always find us. The truth is, as surgeons, we have more chances than most to set the balance in our favor. Yet no matter how hard we try we can't escape our karma. It follows us home. I guess we can't really complain about our karma. It's not an affair. It's not unexpected. It just... evens the score. And even when we're about to do something that we know will tempt karma to bite us in the ass... well, it goes without saying. We do it anyway."

GEORGE

CRISTINA: "You know, [Burke] is acting like I committed a crime. Like my apartment is full of stolen goods. He’s acting like I kept my apartment to hide stolen goods, so I could do illegal organ transplants for money."
MEREDITH: "Are you sure he’s not just acting like you lied to him about moving in?"
CRISTINA: "What the hell's wrong with you?"
MEREDITH: "My mother's a filthy whore."

PRESTON: [enters his apartment] "I am Preston Burke. I am a widely renowned cardio-thoracic surgeon. I am a professional and moreover I am a good, kind person. I am a person that cleans up after himself. I am a great cook. And you? You are an unbelievable slob. A slovenly, angry intern. I am Preston Burke. And you... are the most competitive, guarded, stubborn... the most challenging person I have ever met. And I love you. Why the hell won't you just let me?
CRISTINA: "I gave up my apartment 20 minutes ago."
PRESTON: [pauses] "Well, alright then."

MARK: [walks into the bar] "Is this seat taken?"
MEREDITH: [pauses] "I guess not."
MARK: [sits] "You look sad."
MEREDITH: "I just saw my father for the first time in 20 years."
MARK: "How’d that go?
MEREDITH: "It could have gone better. What’re you still doing here?"
MARK: "I'm hoping Addison shows up."
MEREDITH: "You're still in love with her?"
MARK: "You're still in love with Derek."
MEREDITH: [pauses] "She won't show, you know."
MARK: "No?"
MEREDITH: "He’s not the kind of guy you leave if you can help it."
MARK: "But what if you're wrong? Just this once, what if life comes down on the side of the dirty mistresses?"

[narrating] "I've heard that it’s possible to grow up, I've just never met anyone who’s actually done it. Without parents to defy, we break the rules we make for ourselves. We throw tantrums when things don’t go our way. We whisper secrets with our best friend, in the dark. We look for comfort where we can find it. And we hope against all logic, against all experience, like children, we never give up hope."

MEREDITH

DENNY: "Hey."
IZZIE: "Hey."
DENNY: "Do you believe in karma?"
IZZIE: "Actually, I do."
DENNY: "I think you might be mine."
IZZIE: "Well then you must have been very very good to deserve me."

RICHARD: "I see you in there."
MIRANDA: "No, you don’t."
RICHARD: "Your husband was discharged over an hour ago."
MIRANDA: "I'm not here."
RICHARD: "Go home. You're not working today. You're on maternity leave."
MIRANDA: [shuts door] "Exactly!"

CRISTINA: [referring to George] "What is with him?"
ALEX: "Okay, 50 bucks O'Malley caught her doing McDreamy."
IZZIE: "McDreamy?"
ALEX: "Did I just call the dude McDreamy?"
CRISTINA: "Oh, you know you did."
ALEX: [to Izzie] "You are ruining my life."

[to Meredith, George] "What? So I slept with him again. So I'm a big whore. A big horny whore who can't get enough. Can we get over the shocked silence already?"

IZZIE

CALLIE: "George"
GEORGE: "Hi."
CALLIE: "You didn’t call me."
GEORGE: No I did. I did, a few times. I just hung up every time."
CALLIE: "Nice, George. Very stalker-like."

DENNY: "Hey. Don’t you have somewhere to be?"
IZZIE: "Yeah. Yeah I do. I’m there."
DENNY: [smiles] "Good."

[corners George in elevator] "You’re trapped. You you don’t have to talk. I’ll do the talking, George. I am truly, very deeply sorry. I’m not going to make excuses, I’m just sorry. Look... I know you’re going to get off this elevator and walk away and not look back. But George, we're friends, real friends. And that means, no matter how long it takes, when you finally do decide to look back, I’ll still be here."

MEREDITH

Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

I want to marry you. I want to have kids with you. I want to build us a house. I want to settle down and grow old with you. I want to die when I'm 110 years old, in your arms. I don't want 48 uninterrupted hours. I want a lifetime. Mmm. Do you see what happens? I say things like that and you fight the urge to run in the opposite direction. It's okay, I understand. I didn't, but now I do, I do. You're just getting started and I've been doing this for a long time now. Deep down, you're still an intern, and you're not ready.

Derek