Optimism for the win!

Maggie

I told you to keep that baby in!

Arizona

Bailey: You and Derek went down in a plane, you drowned, he got shot, you gave birth in a power outage...
Meredith: Is this supposed to make me feel better?
Bailey: I'm just saying, you have every reason to be distracted. Every reason to think the sky is falling.

There ought to be some rule, you know? People who have been in a plane crash can't work on one.

Alex

Amelia: I don't have any more to give. I'm not trying to hurt you.
Owen: I'm not hurt. I get it. And I'm done.

I'll accept the risk. Because you are worth it. Because you matter to me. Because I love you. And I'm not going anywhere.

Richard

Now, I don't know what personal stuff is going on between the two of you exactly, but whatever it is, I will not allow it to compromise my patient, his care, or his penis. And for what it's worth, I think you two are good together. Also Catherine Avery is my mother-in-law, so I'll call her any damn time I feel like it!

April

You know, for the record, I only thought about maiming you once, Callie. And I told you the second I thought about it.

Arizona

You know, cutting off a penis isn't actually that big of deal. I mean, it's not like he needs it for survival or I don't know, to walk.

Arizona

I looked down at that miracle in my hand, and I just knew. General surgery had chosen me. Well, one day, you'll know.

Richard

All my orgasms are gonna be self-made, hand crafted ones.

Maggie

Amelia: Owen and I are getting to know each other.
Meredith: How well? Pants on or pants off well? Is it just sex, or is there something more?

Grey's Anatomy Quotes

MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)