A surgeon must always be prepared to lose, and in neurosurgery, with the big tumors, we lose those battles as often as we succeed. The key though, win or lose, is to never fail, and the only way to fail is not to fight. So you fight until you can't fight anymore.

Amelia

Dr: Herman: I wanted to break new ground. I wanted to leave a legacy. I wanted my life, my brain, my existence to mean something. The thing I never really thought about though, the thing I never really wrapped my brain about until now was in order to do that, in order to be remembered, in order to leave something significant behind, you have to leave.

This is history. This surgery is history. How could I not be excited about that?

Amelia

This tumor is fierce, intimidating and aggressive, but so am I.

Amelia

Charming, isn't it? They put clouds on the ceiling to distract you. The least they could do is put up something interesting like porn.

Dr. Herman

My life is so much better now that I have nothing. I can't recommend a tumor, but you should try it.

Dr. Herman

It's her song. So, get off the stage and let her sing it.

Bailey

Residents gone wild!

Dr. Herman

He squeezed my finger and then he let go.

April

If you aren't willing to keep looking for light in the darkest of places without stopping even when it seems impossible, you will never succeed.

Amelia

Do you believe in God? It's okay, you can believe for the two of you. You have lost somebody, and you are hurting, but you will get through this. You can survive this. You are strong. It's okay. You are going to be okay, I promise.

April

God, I don't know if you're out there or not, or if you can even hear people that don't know you're out there, or if you give a crap about what they say, but God, Yahweh, ET, Buddah, whatever... April knows. She knows, right? She believes and she needs you, so show up for her? Please? Show up for April. She loves you. She needs you. Please, show up for her. Please.

Jackson

Grey's Anatomy Quotes

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.

Meredith

Callie: Did anyone ever think you two were a couple?
Meredith: No, because we screw boys like whores on tequila.
Cristina: Then we either try to marry them or drown ourselves.
Callie: Huh.