"You think... you think you know someone, know who they are. You share a house and make wishes on eyelashes with them and we don't know each other, none of us. We're just a bunch of interns who work together. There's nothing there!"

IZZIE

DEREK: "It's okay."
MEREDITH: "It's not okay. You have a wife who's not easy to hate. Who's annoyingly kind and painfully smart, and currently saving my friend's life."

"I've been sitting home for a week watching Oprah give away things on T.V. Oprah, Derek!"

RICHARD

MIRANDA: "Go take care of Dr. Grey."
GEORGE: [hugs her] "Yes. Thank you. She needs a friend right now."
MIRANDA: [silence]
GEORGE: "Oh... her mother."

IZZIE: "Why do you do that?"
ALEX: "Do what?"
IZZIE: "Act like an ass whenever any one but me is around. They hate you enough as it is."

BAILEY: "Izzie, both Dr. Shepherds need an intern up on ICU."
IZZIE: "Wait... both of them, together? Me, by myself, with the two married people who hate each other?"
BAILEY: "Go. Cristina, you're on the thoracotomy."
CRISTINA: "With Burke? I can't have the hateful married couple instead?"

MEREDITH: [to Derek] "Stop talking to me like you're my boyfriend. Stop talking to me... at all!" [Storms out]
ALEX: "Dude, that was rough."

MIRANDA: "Do you have a problem?"
IZZIE: "No."
MIRANDA: "Do you have a mocha latte?"
IZZIE: "No."
MIRANDA: "Then go away."

[narrating] "Surgeons are control freaks. With a scalpel in your hand, you feel unstoppable. There's no fear, there's no pain. You're 10 feet tall and bulletproof. And then you leave the O.R. All that perfection, that beautiful control, just falls to crap."

MEREDITH

[narrating] "A wise man once said you can have anything in life if you will sacrifice everything else for it. What he meant is nothing comes without a price. So before you go into battle, you better decide how much you're willing to lose. Too often, going after what feels good means letting go of what you know is right, and letting someone in means abandoning the walls you've spent a lifetime building. Of course, the toughest sacrifices are the ones we don't see coming, when we don't have time to come up with a strategy to pick a side or to measure the potential loss. When that happens, when the battle chooses us and not the other way around, that's when the sacrifice can turn out to be more than we can bear."

MEREDITH

[to George] "Remember the good old days? When you lived with us, when you used to tell me stuff. Like... where you live?!"

IZZIE

IZZIE: "You're tall."
DENNY: "I know."

Grey's Anatomy Season 2 Quotes

IZZIE: "You want us to make her seize? How do we make someone have a seizure?"
DEREK: "Get creative. Do some research."
GEORGE: "Well, if all the normal methods have failed then what are we supposed to do-"
DEREK: "Use a strobe light. Get her drunk. Hang her up upside down from the ceiling and hit her with a wiffle ball bat, for all I care. Just make her seize. 'Cause until she seizes, I don't know when to operate, and if I don't know when to operate, I can't get this woman out of my life. And this woman is not how I like to start my mornings."

CRISTINA: "I am a 55 year old man. I'm nauseous and I can't stop throwing up."
ALEX: "Forget it, alright. I didn't ask for anybody's help."
CRISTINA: "Look, evil spawn, you can nurse your pride -- the key word being nurse -- or you can pass your test and be a doctor. Up to you."
ALEX: [pauses] "Any abdominal pain?"
CRISTINA: "Yes, from my giant fat belly all the way to my back. Oh, and I'm drunk. Hiccup. Hiccup."