"Yes, he made some mistakes, but he’s not a monster. He’s just an inarticulate person that spills food on his shirt... a lot."

SUSAN

ALEX: [about Izzie] "What's her problem?"
CRISTINA: "Still drunk."

GEORGE: "Izzie."
IZZIE: "George."
GEORGE: "What the hell happened last night? Did I at least call Callie before I passed out?"

IZZIE: "What if it's God's plan?"
ADDISON: "So... God wants you to be an adulterer?"

[narrating] "The thing about plans is they don't take into account the unexpected, so when we're thrown a curve ball, whether its in the O.R. or in life, we have to improvise. Of course, some of us are better at it than others. Some of us just have to move on to plan B, and make the best of it. And sometimes what we want is exactly what we need. But sometimes, sometimes what we need is a new plan."

MEREDITH

"Let's meet the contenders. Let's see. This is, this is Maggie. Married a high school sweetheart and has two kids. Loves being a mom. Coaches her daughter's basketball team. And makes an insane banana cream pie. And this is Elizabeth. Graduated from Northwestern. Met her husband at a political rally where they got arrested and fell in love. She's all angry and fired up, but everyone forgives her cause she means well. This, one, this one is Ava. She's funny, she's tough and a little neurotic sometimes, but you get used to it. You can tell she's been through a lot in her life, but it only made her stronger, you know?"

ALEX

MARK: "What do do you consider your weaknesses?"
ADDISON: "I don't have any. I'm that good. What are yours?"
MARK: "I'm an easy mark for evil redheads."

MEREDITH: "How was your interview?"
DEREK: "Not great. It wasn't great. I was distracted."
MEREDITH: "By what?"
DEREK: "Nothing. I don't know."
MEREDITH: "On a scale of 1 to 10 how bad is it?"
DEREK: "Eight."
MEREDITH: [kisses him] "How about now?
DEREK: "Seven."
MEREDITH: [kisses him] "How about now?"
DEREK: "Six... five... four... three..."

MEREDITH: "I let Mark use the memory of my mother to win points with the Chief. You were right."
DEREK: "I'm sorry."
MEREDITH: "You know what's weird?"
DEREK: "What's weird?"
MEREDITH: "It's exactly what she would have wanted."
DEREK: "Dead mommy's proud?"
MEREDITH: "Dead mommy's proud."

"Sorry. I'm so sorry."

GEORGE

IZZIE: "Hours. Hours of out life that are all I can think about and you seriously can't remember?"
GEORGE: "Look, Izzie, I was drunk. Whatever I did, whatever I said, I'm sure I didn't mean it."
IZZIE: "Yes, George, you meant it. You meant it a lot. You meant it more than once."

"Nobody, meaning me, needs to hear George's rendition of 'SexyBack' at 3 in the morning."

CRISTINA

Grey's Anatomy Season 3 Quotes

[narrating] "Too often, the thing you want most is the one thing you can't have. Desire leaves us heartbroken, it wears us out. Desire can wreck your life. But as tough as wanting something can be. The people who suffer the most, are those who don't know what they want."

MEREDITH

CRISTINA: "There's a club. The Dead Dads Club. And you can't be in it until you're in it. You can try to understand, you can sympathize. But until you feel that loss... My dad died when I was nine. George, I'm really sorry you had to join the club."
GEORGE: "I... I don't know how to exist in a world where my dad doesn't."
CRISTINA: "Yeah, that never really changes."