Why won't you ever let me be happy?

Debbie [to Fiona]

Fiona: You can't have a boy in your bed!
Debbie: Why not? You do!
Fiona: I am a grownup.
Debbie: I'm pregnant!
Fiona: No you're not. No you're not.

Amanda: Does she make you happy or is it just about the sex?
Lip: Sex, mostly.

Bianca: Let's go get drunk and buy a gun.
Frank: A gun?
Bianca: Yeah.

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Fiona: So are you and Kev...
V: Giving it another try.

There's always gonna be people that are going to try and fix us and you can never make those people happy, like it breaks their heart just to look at you.

Monica [to Ian]

We should clarify something, because for me personally, part of feeling alive is being alive!

Frank [to Bianca]

V: You know, having a Russian sex worker isn't ideal for child care.
Kev: Yeah, but she does come in handy.

I know! Lets get crack!

Bianca [to Frank]

I'm not homeless, I told you. I have a home, I'm just not welcome there.

Frank [to Bianca]

Family sucks ass!

Sammi

Bianca: I'm not gonna be alive to pay off my credit card, what does it matter?
Frank: Such wisdom for one so young.

Shameless Quotes

When you're poor, the only way to make money is to steal it or scam it.

Lip

We’re all addicts Fiona, trying to fill a void. Some of us are just better at hiding it, right?

Robbie