When I was human I had to eat constantly. It was kind of annoying.

Castiel

I'm saying, you want to work, let’s work. If you want to be brothers... those are my terms.

Sam

Crowley: Jerk.
Dean: Bitch.

I'm a man of my word.

Dean

I will save my brother or die trying.

Sam

I'm sensing awkwardness.

Castiel

There’s no trade. There’s no meet-up, no nothing except the 100 percent guarantee that somewhere down the road I will find you, and I will kill you.

Dean

Crowley: He’s my best friend, my partner in crime. They’ll write songs about us, graphic novels: The Misadventures of Crowley and Squirrel. Dean Winchester completes me. And that’s what makes you lose your chickens.

Yeah, you're that guy from that thing.

Dean

You sound like a Viagra commercial, you know that, right?

Dean

Castiel, I think the Winchesters are a bad influence on you.

Hannah

Dean: Do I know you?
Becky: No, but I know you.

Supernatural Quotes

Why do they call this place The Empty? It's full. It's full of sorrow and despair playing over and over again of angels and demons dreaming about their regrets. Forever.

Ruby

Weird, creepy, off-the-grid "Children of the Corn" people? Yeah, I’m in.

Dean