Dean: You need my consent. Michael needs my say-so to ride around in my skin.
Zachariah: Unfortunately, yes.
Dean: Well, there's got to be another way.
Zachariah: There is no other way. There must be a battle. Michael must defeat the Serpent. It is written.
Dean: Yeah, maybe. But, on the other hand... eat me. The answer's no.

Zachariah: You're Michael's vessel. Or rather, his receptacle.
Dean: I'm a vessel?
Zachariah: You're the vessel. Michael's vessel.
Dean: How? Why, why me?
Zachariah: Because you're chosen! It's a great honor, Dean.
Dean: Oh, yeah. Life as an angel condom. That's real fun. I think I'll pass, thanks.

Zachariah: I see you told the demons where the sword is.
Dean: (deadpan) Oh, thank God. The angels are here.

Sam: I brought this on.
Bobby: You're damn right you didn't listen. You were reckless and selfish and arrogant.
Sam: I'm sorry.
Bobby: Oh, yeah? You're sorry you started Armageddon? This kind of thing don't get forgiven, boy. If, by some miracle we pull this off... I want you to lose my number.

Sam: Becky, does he know where it is?
Becky: In a castle on a hill made of forty-two dogs.
Dean: Forty-two dogs?
Sam: Are you sure you got that right.
Becky: It doesn't make sense, but that's what he said. I memorized every word... for you.
Sam: Umm... Becky, can you... quit touching me?
Becky: No.

Oh god. Is that a molar? Do I have a molar in my hair. This has been a really stressful day.

Chuck

Dean: Where's Cass?
Chuck: He's dead. Or gone. The archangel smote the crap out of him. I'm sorry.
Dean: You're sure? I mean, maybe he just vanished into the light or something.
Chuck: Oh, no. He exploded. Like a water balloon of chunky soup.

Dean: Do I know you?
Becky: No, but I know you.

Supernatural Season 5 Quotes

Dean: Where's Cass?
Chuck: He's dead. Or gone. The archangel smote the crap out of him. I'm sorry.
Dean: You're sure? I mean, maybe he just vanished into the light or something.
Chuck: Oh, no. He exploded. Like a water balloon of chunky soup.

Dean: Do I know you?
Becky: No, but I know you.