Wolowitz: This is the thing from the pizza box that keeps the lid from touching the cheese.
Raj: Is that what this is for? In India, the lid just touches the cheese. Of course, we also have rampant poverty and periodic outbreaks of chlorea so a little cardboard on our cheese is no biggie

Sheldon: Why does Leonard get to go?
Wolowitz: Because he's upset over his situation with Penny, and if I have to hear about it again, I'm gonna kick him in his ovaries

If you really want to clean up your Karma, go get my fricking latte

Raj [to Leonard]

I have to say I thought the toilet humor would get less funny with repetition. Apparently there is no law of diminished comedic returns when it comes to space poop

Sheldon

Sheldon: You have to check your messages, Leonard! Leaving a message is one-half of a social contract, which is completed by the checking of the message. If that contract breaks down, then all social contracts break down and we descend into anarchy.
Leonard: It must be hell inside your head.
Sheldon: At times.

Raj: Interesting. Penny's current suitor asking advice from Penny's former suitor.
Leonard: Thanks for close-captioning my pain, Raj.

Stuart: Here Sheldon. I pulled the new Hellboy for you. It's mind-blowing.
Sheldon: Excuse me! Spoiler alert!
Stuart: What? I didn't spoil anything.
Sheldon: You told me it's mind-blowing, so my mind is going into it pre-blown. Once a mind is pre-blown, it cannot be re-blown.
Stuart: I'm sorry.
Sheldon: Said the Grinch to Christmas.

The Big Bang Theory Season 2 Episode 22 Quotes

Raj: Interesting. Penny's current suitor asking advice from Penny's former suitor.
Leonard: Thanks for close-captioning my pain, Raj.

Stuart: Here Sheldon. I pulled the new Hellboy for you. It's mind-blowing.
Sheldon: Excuse me! Spoiler alert!
Stuart: What? I didn't spoil anything.
Sheldon: You told me it's mind-blowing, so my mind is going into it pre-blown. Once a mind is pre-blown, it cannot be re-blown.
Stuart: I'm sorry.
Sheldon: Said the Grinch to Christmas.