Wolowitz: Women, huh? Can't live with 'em; can't successfully refute their hypotheses.
Sheldon: Amen to that.

Someday, when you have varicose veins, I'll show you how to massage them.

Wolowitz

Despite their tendency to build Death Stars, I've always been more of an Empire man.

Sheldon

Penny: God, he's an ass when he drinks.
Wolowitz: He's an ass he doesn't. You just don't hear it.

Leonard: Amy is judgmental, sanctimonious, and frankly just obnoxious
Sheldon: So?
Leonard: So we already have you for all that.

Sheldon: One has to navigate a labyrinth of social nonsense before one could be fed here
Amy: Really? I assumed an establishment named Cheesecake Factory would function more efficiently.
Sheldon: It's how they lure you in. I believe it's called, "bait and switch."

I just run till I'm hungry, and then I stop for a bear claw.

Penny

Lenny: I though you hate dogs.
Sheldon: A dog-opus can play fetch with eight balls. No one can hate that.

Leonard: Penny, Steve Wozniack was one of the co-founders of Apple computer. He and Steve Jobs...
Penny: Yeah. I know who he is. I watch Dancing With the Stars.

Oh look! It's Leonard and R2-D-bag.

Wolowitz

Penny: Honey, have you ever run before?
Sheldon: Certainly. I've run from bullies, dogs, angry chickens and one particularly persistent PE teacher determined to bend me over and give me a scoliosis test.

Sheldon: I don't understand why you're not enjoying this. Together, in this car, with my enhanced capabilities, we're like 'Knight Rider.'
Leonard: Except, in Knight Rider, the car isn't a yammering sphincter.
Sheldon: You mock the sphincter, but, the sphincter is a class of muscle without which human beings couldn't survive. There are over 50 different sphincters in the human body. How many can you name?
Leonard: I was wrong. This is exactly like Knight Rider

TBBT Quotes

Oh, Bernadette, please play my clarinet.

Raj's poem

Sheldon: I'll have a diet Coke.
Penny: Can you please order a cocktail? I need to practice mixing drinks.
Sheldon: Fine... I'll have a virgin Cuba Libre.
Penny: That's... rum and Coke without the rum.
Sheldon: Yes, and would you make it diet?