No one calls me Moon Pie but Meemaw!

Sheldon

I'm sorry, coffee's out of the question. When I moved to California I promised my mother that I wouldn't start doing drugs.

Sheldon

There once was a brave lad named Leonard, with a fie fie fiddle dee dee. He faced a fearsome giant while Raj just wanted to pee.

Sheldon (singing)

Wolowitx: You think you can put up with Sheldon?
Raj: Well I'm a hindu. My religion teaches that if we suffer in this life, we're rewarded in the next. Three months in the north pole with Sheldon and I'm reborn as a well hung billionaire with wings

Leonard [about snuggie gift]: what does this mean?
Penny: Wine, credit cards and late night television are a bad combination

But if we were part of the team that confirmed string theory, we could drink for free in any bar in any college town with a university that has a strong science program!

Raj

Wolowitz: Just imagine ... if he says yes, we'll have an entire summer without Sheldon.
Raj: We could play outside.
Wolowitz: We could sit on the left side of the couch.
Leonard: I could use the bathroom at 8:20!
Raj: Our dreams are very small, aren't they?

Sheldon: It must be an emergency; everyone at the university knows that I eat my breakfast at 8 and move my bowels at 8:20
Leonard: Yes, how did we live before Twitter?

Wolowitz: This is the thing from the pizza box that keeps the lid from touching the cheese.
Raj: Is that what this is for? In India, the lid just touches the cheese. Of course, we also have rampant poverty and periodic outbreaks of chlorea so a little cardboard on our cheese is no biggie

Sheldon: Why does Leonard get to go?
Wolowitz: Because he's upset over his situation with Penny, and if I have to hear about it again, I'm gonna kick him in his ovaries

If you really want to clean up your Karma, go get my fricking latte

Raj [to Leonard]

I have to say I thought the toilet humor would get less funny with repetition. Apparently there is no law of diminished comedic returns when it comes to space poop

Sheldon

The Big Bang Theory Season 2 Quotes

Sheldon [to Kripke]: Also, I am given to understand that your mother is overweight.
Raj: Oh, snap.
Sheldon: Now of course, if that is the result of a glandular condition and not sloth and gluttony then I withdraw that comment.

How is "doable" anything but a compliment?

Wolowitz