Cathy: You know, you can't hate black people, right?
Marlene: I don't. I just need to get angry sometimes.

You're the yin to my yang, the ping to my pong, the normal to my crazy. Let's be us together.

Paul

Cancer sucks. Put that in your God damned inspirational poster!

Cathy

Adam: I want my life to be normal.
Andrea: I want to meet Usher. Think that's gonna happen?

What are those tiny hot dogs? You white folks eat some crazy ass food.

Andrea

Cathy: Think of how great you're gonna feel when you go down a dress size?
Andrea: Who the fuck wears dresses?

You should come, too. I would love to get to know any girl that would date my homeless brother.

Cathy

Cathy: You're an asshole.
Sean: I'm surprised you know what one looks like since you didn't take a shit for most of high school.

You wear baggies for shoes, Sean. You're so not allowed to say anything is embarrassing.

Cathy

Adam: You should't say chill-ax. It's gay!
Cathy: Don't use gay like that!

Paul: Angela says you're holding me emotionally hostage.
Cathy: Tell Angela she's sort of a bitch.

Cathy: I wanna do it on the grass.
Paul: Really? You want me to do you in the ass?
Cathy: No! GRASS!

The Big C Season 1 Quotes

Sean: The last you could do is buy a damn Hybrid.
Cathy: The least you could do is take a shower.

Paul: Can we at least figure out what to tell Adam? Because right now, my story is: "Adam, your mom's a meanie!"