My lifestyle is my retirement plan.

Homer

They don't call me "Springfield Fats" just because I'm morbidly obese!

Homer

What kind of civilized people eat the body and blood of their savior?
[camera pans to Reverend Lovejoy...]

Marge

Oh, fudge. That's...broken. Fiddle dee dee. That will require a tetanus shot. I'm not going to swear, but I am going to...kick this dog house down!
Homer goes into a rage.)

</i> Homer

Lisa: Congratulations. You're officially a sociopath.
Bart: At least I'm on a path.

Behold! I am Captain Kirk from Star Trek 1! 2 ... 5 ... Generations ... Boston Legal.

Comic Book Guy

Moe: Pretty much if it moves, you can bet on it.
Homer: What about the Detroit Lions?
Moe: Hey, lay off Detroit. Them people is livin' in Mad Max times.

If I wanted to pay for commercials I can't skip, I'd sign up for Hulu Plus.

Homer

I moved here because on a calculator, the ZIP Code spells "boobs."

Moe

Son, a woman is a lot like a... a refrigerator! They're about six feet tall, 300 pounds. They make ice, and um Oh, wait a minute! Actually, a woman is more like a beer. They smell good, they look good, you'd step over your own mother just to get one! But you can't stop at one, you wanna drink another woman!

Homer

Sideshow Bob has no decency, he called me, Chief Piggum! (everybody laughs) Oh ah, now I get it! Haha, that's good!

Chief Wiggum

Ralph: What's a battle?
Principal Skinner: Hahahaha, lets go.
Superintendent Chalmers: Did that boy say what's a battle?
Principal Skinner: No he said What's that rattle, it's about the heating duct.
Superintendent Chalmers: Hmm, it sounded like battle.
Principal Skinner: I've had a cold, so--
Superintendent Chalmers: Oh so you hear r's as b's?

The Simpsons Quotes

Officer Eddie: (reading Steve Sax's license) Well well, Steve Sax, from New York City.
Officer Lou: I heard some guy got killed in New York City and they never solved the case. But you wouldn't know anything about that now, would you, Steve?
(Lou and Eddie laugh)
Steve Sax: But there are hundreds of unsolved murders in New York City.
Officer Lou: You don't know when to keep your mouth shut, do you, Saxxy Boy?

Wow, now I see why they call you Miss Hoover. You must have been vacuuming for an hour.

Bart