Brian and Stewie
Family Guy Season 8 Episode 17 (05/02/10)
Brian and Stewie get locked in a bank vault for 2 days during the 150th episode of Family Guy. After making Brian eat his poop out of his dirty diaper and getting drunk together, Stewie eventually admits Brian is the only person that makes his life tolerable and that he loves him. Brian admits the love is reciprocated.