Peter's sick, and it gives him a deep, gravelly voice that Lois finds irresistible  When he gets it back, Lois doesn't find it so attractive, so Peter tries to get sick again. He just winds up in the hospital instead of getting his raspy voice back, so he dispatches Lois to compete on his bowling team for him. She ends up being an able replacement, as she helps Joe and Quagmire win. The three of them hang out afterward, and it turns out Lois is a better fit with the gang than Peter, though he starts to feel left out. Lois gives up her new friendships to make her husband happy.

Meanwhile, Stewie loses his teddy bear Rupert due to a factory recall, and the replacement stuffed giraffe he's sent doesn't make him as happy. So he and Brian go to the factory he was recalled to, and they save Rupert from being burned. Stewie hugs Rupert when he gets home, but the bear's eyes pop out, choking Stewie to death - the exact thing the bears were recalled for.