"In the Midnight Hour"

Why the heck are the interns cutting themselves? And why the heck is Izzie still seeing Denny? And what happens when it all goes wrong?

"These Ties That Bind"

As if this season weren't turbulent enough, it's time for a couple of newcomers - Harriet Dixon and intern Sadie - to make their debuts and shake things up at Seattle Grace.

"Rise Up"

The sudden revelation that this is Brooke Smith's (Erica Hahn) last episode has dominated the discussion and speculation of this episode so far.

"Life During Wartime"

Empowered by the Chief, Bailey has new responsibility and the new head of trauma - Owen Hunt - is shaking things up at Seattle Grace.

"There's No 'I' in Team"

Mark talks with Callie about love. Seriously. Bailey heads a risky surgery - even by Seattle Grace standards. Derek gets sole credit for a tumor study he and Mer did.

"Brave New World"

Meredith freaks when Derek discovers her mother's diary, Callie preps for a date with Erica, and Cristina stumbles into a new part of the hospital.

"Here Comes the Flood"

In case the title didn't give it away, Seattle Grace is hit by a flood in this episode. Or more accurately, a plumbing fiasco.

"Dream a Little Dream of Me"

Meredith and Derek soon discover that 'happily ever after' isn't that easy, a military doctor, Dr. Owen Hunt, catches Cristina's eye, an...

"Freedom"

As the fourth season finale gets underway, Meredith Grey works with Dr. Wyatt to understand what her mother was trying to tell her when ...

"Losing My Mind"

Richard's mentor is coming in for surgery and he wants top priority given to it. Derek and Meredith's patient, who is about to undergo a...

Grey's Anatomy Quotes

CRISTINA: "There's a club. The Dead Dads Club. And you can't be in it until you're in it. You can try to understand, you can sympathize. But until you feel that loss... My dad died when I was nine. George, I'm really sorry you had to join the club."
GEORGE: "I... I don't know how to exist in a world where my dad doesn't."
CRISTINA: "Yeah, that never really changes."

MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."