"Before and After"

Addison, Naomi and Sam rush to Seattle Grace with Archer and reunite with old friends Derek and Mark. Izzie employs her fellow doctors in a medical game. Owen runs into someone from his past.

"Beat Your Heart Out"

In "Beat Your Heart Out," Derek searches for the best way to pop the question to our girl, while Little Grey wants to go public with Big Sloan.

"Stairway to Heaven"

As a patient's condition becomes more and more dire, Bailey becomes more and more desperate to do something - anything - to save him.

"Sympathy for the Devil"

Death row inmate William is still around and he's shaking things up, while Derek's mother comes to Seattle Grace and meets Meredith for the first time.

"Wish You Were Here"

Grey's Anatomy returns from its holiday hiatus with its 11th episode of Season Five.

"All By Myself"

Dr. Yang is forced to give up the coveted solo surgery, while sparks between Mark and Lexie possibly heat up.

"In the Midnight Hour"

Why the heck are the interns cutting themselves? And why the heck is Izzie still seeing Denny? And what happens when it all goes wrong?

"These Ties That Bind"

As if this season weren't turbulent enough, it's time for a couple of newcomers - Harriet Dixon and intern Sadie - to make their debuts and shake things up at Seattle Grace.

"Rise Up"

The sudden revelation that this is Brooke Smith's (Erica Hahn) last episode has dominated the discussion and speculation of this episode so far.

"Life During Wartime"

Empowered by the Chief, Bailey has new responsibility and the new head of trauma - Owen Hunt - is shaking things up at Seattle Grace.

Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

There's a reason I said I'd be happy alone. It wasn't 'cause I thought I'd be happy alone. It was because I thought if I loved someone and then it fell apart, I might not make it. It's easier to be alone, because what if you learn that you need love and you don't have it? What if you like it and lean on it? What if you shape your life around it and then it falls apart? Can you even survive that kind of pain? Losing love is like organ damage. It's like dying. The only difference is death ends. This? It could go on forever.