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We'll post a detailed recap of this episode soon after it airs. In the meantime, here's a preview for it:

A patient with both male and female DNA has the team stumped. Also, House starts acting - gulp! - nicely, raising Cuddy's and Wilson's suspicions that something is terribly wrong.

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House Season 5 Episode 16 Quotes

Dr. Cuddy: The parents haven't told their son that he could have been their daughter. They want assurance that we won't either.
House: Less fun, but still.

(to Jackson's parents) You gave birth to a freak of nature. Doesn't mean it's a good idea to treat him like one..