Wealthy, terminally ill Chelsea Rossberger is murdered with an air embolism in her bed even as her IV bag was dripping enough morphine to allow her to die peacefully.
The team investigates and finds that Brad, the chauffeur was actually her late husband's son. He was so angry at Chelsea for denying him access to his late father that he wanted to make sure she died painfully instead of at peace.
When Jane has to cancel a doctor's appointment, Angela goes instead and asks about being her midwife leading to a long talk between mother and daughter about boundaries.
Jane, Korsak, and Frankie all must come to terms with Detective's empty desk and that he's not coming back to it.
Maura resists a romantic entanglement with a handsome professor because her last boyfriend was a serial killer. With prodding from Jane, Angela, and Jack himself, Maura decides to give him a chance.