Damon begged Jules for a cure for Rose's wolf bite this week, but the latter simply talked trash about the awful, inevitable death in store for Damon's new friend. And she wasn't kidding, either:

Rose had a fever, she hallucinated, she killed innocent people. In the end, Damon had to put her out of her misery and drive a stake through her heart. This affected him greatly, as he was driven to drink and approach a random woman at the end of the episode. He admitted to her that he missed being human - and then he bit into her neck.

Elsewhere:

- Stefan is trying to acclimate himself to vervain. He also wants to get in touch with Isobel so he can learn about Klaus. But after trying a number Alaric gave him for her, Stefan tracks down John instead. Elena's father says hello to her near the end of the hour.

- Both Matt and Tyler kiss Caroline. Supernatural love triangle alert!

- Jules tells Tyler she wants to help and protect him, that other werewolves are on the way and that Caroline lied: there are many vampires in town, and they are responsible for Mason's death.