Series star Emma Kenney said, "As I called my manager to quit working on Roseanne, I was told it was cancelled. I feel so empowered by @iamwandasykes , Channing Dungey and anyone at ABC standing up for morals and abuse of power. Bullies will NEVER win."

"Today is one of the hardest in my life," series star Michael Fishman wrote in a note posted to Twitter.

"I feel devastated, not for the end of the Roseanne show, but for all those who poured their hearts and souls into our jobs, and the audience that welcomed us into their homes."

"Roseanne’s recent comments about Valerie Jarrett, and so much more, are abhorrent and do not reflect the beliefs of our cast and crew or anyone associated with our show," said series star Sara Gilbert. "I am disappointed in her actions to say the least."

“On behalf of all the writers and producers, we worked incredibly hard to create an amazing show,” Helford says in a statement released through his agent.

“I was personally horrified and saddened by the comments and in no way do they reflect the values of the people who worked so hard to make this the iconic show that it is.”

"The terrible part is all of the talented innocent people who worked on that show now suffer because of this," Rhimes began in her Twitter statement."

"#notjustice But honestly she got what she deserved. As I tell my 4 year old, one makes a choice with one’s actions. Roseanne made a choice. A racist one. ABC made a choice. A human one."

"Roseanne was making boatloads of $ for @DisneyABCTV," said the Supernatural star.

"For them to cancel it because of Roseanne’s racist, xenophobic rants on twitter shows a great deal of corporate responsibility & just how powerful the public’s outrage can be! Keep raising your voices!"

"I just heard #rosanne is cancelled," said the Will & Grace star. "My reaction— tears. I am so relieved and grateful."

"The hate that has been spewing from those in Trump’s orbit has really taken a toll on all of our souls and psyches."

"I didn’t believe it would happen. I had lost faith. Thank you @abc."

Tom Arnold said of Roseanne's cancellation:

"Ton of respect for Bob Iger. Tough decision with financial consequences for his company but right for America....umm..now don't bug Bob but maybe someone else find out if I'm still banned from all of @ABCNetwork for calling Roseanne Barr out first on her racist conspiracy tweets?"

"Brava Channing Dungey," said actress Audra McDonald upon hearing Roseanne was canceled by ABC.

"Aaaaannnd cue the people who just celebrated the NFL targeting player protests defending Roseanne Barr now on 1st amendment grounds. 3,2,1....popcorn," said Jeffrey Wright following Roseanne's cancellation.

"Hey @therealroseanne, just wanted to say- Na Na Na Na," said Younger actor, Aasif Mandvi as he captioned a photo with Valerie Jarrett.

"Hey Hey- eh. Goodbye! #ValerieJarrett #RoseanneCancelled."

"I'm glad Roseanne is canceled," Kumail Nanjiani.

"The backlash to its cancellation is going to be a deafening nightmare."

"Nothing good has come of this entire thing."

"Roseanne Barred," said Gervais, taking a jab at Barr following Roseanne's cancellation.

"adios Roseanne! good riddance. hashtag NOT Winning. the runway is now clear for OUR reboot," said Sheen, shamelessly plugging a potential Two and a Half Men reboot.

"Thank you Channing Dungey!" said the How to Get Away with Murder star.

"Kudos to @ABCNetwork for their quick, decisive actions," said the actress at the top of her tweet.

"We live in a country where you can express yourself freely, but that doesn’t mean there aren’t consequences for hateful speech and actions."