Ready for The Amazing Race All-Stars? The show's new cast poses for a promotional photo here.

William "Bopper" Minton and Mark Jackson are very good friends. They hail from Kentucky, are unemployed and are racing to raise money for Bopper's sick daughter and to raise awareness about Clay County, the third-poorest county in the U.S.

Joey Graceffa and Meghan Caramena are total BFFs and host a YouTube show together. They finished fifth on Season 22.

Natalie Anderson and Nadiya Anderson hail from New Jersey and finished four on Season 21. Can you tell they're related?

Margie O'Donnell and Luke Adams are mother and son. They communicate via sign language because the latter is deaf.

John Erck and Jessica Hoe are from Minnesota and they are engaged. They finished ninth on season 22.

These Harlem Globetrotters finished fourth on season 15. They were major fan favorites.

David O'Leary and Connor O'Leary finished eighth on Season 22. They have both survived cancer.

The Cowboys are back! This will mark the third Amazing Race appearance for Cord McCoy and Jet McCoy.

Jennifer Wayne and Caroline Cutbirth are good pals and country singers. They came in fourth on Season 22.

Brendon Villegas and Rachel Reilly are newlyweds! The latter actually won Season 13 of CBS's Big Brother.

Leo Temory, 27, and Jamal Zadran, 26 finished in fourth place on Season 23. They call themselves the Afghanimals.