On the third episode of the 20th season (!) of The Simpsons, Bart somehow changes roles with another man and as he arrives at his new home (among McMansions) he catches a brief glimpse of our very own McDreamy and McSteamy ... animated of course.
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Sadie arrives and Meredith is happy to see her. Derek and Cristina lament that this supposed close friend of hers is here.
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Derek confronts Owen about a patient, then pleads with Callie for help.
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Guest star Mary McDonnell plays Dr. Harriet Dixon, a renowned cardiac surgeon who suffers from Asperger's syndrome.
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Bailey tells Dr. Dixon about the transplant patient ... and she puts Alex in his place for his terminology.
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Sadie talks to Meredith about her arrival, and what she's been up to for the past couple of years.
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A promo for the eighth episode of Season Five of Grey's Anatomy, "These Ties That Bind."
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Callie and Erica fight over Izzie, and Erica leaves - presumably for good.
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Grey's Anatomy Quotes

Just because we can live without something, it doesn't mean we have to.

Meredith

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)