Guest star Mary McDonnell plays Dr. Harriet Dixon, a renowned cardiac surgeon who suffers from Asperger's syndrome.
Added:
Bailey tells Dr. Dixon about the transplant patient ... and she puts Alex in his place for his terminology.
Added:
Sadie talks to Meredith about her arrival, and what she's been up to for the past couple of years.
Added:
A promo for the eighth episode of Season Five of Grey's Anatomy, "These Ties That Bind."
Added:
Callie and Erica fight over Izzie, and Erica leaves - presumably for good.
Added:
Cristina and Alex get a tongue-lashing from Hunt over their treatment of a patient, but then Cristina opens up to Owen.
Added:
The residents meet a new "patient" - and learn an important piece of news.
Added:
Cristina and Owen get into it over the big surgery.
Added:

Grey's Anatomy Quotes

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.

Meredith

Callie: Did anyone ever think you two were a couple?
Meredith: No, because we screw boys like whores on tequila.
Cristina: Then we either try to marry them or drown ourselves.
Callie: Huh.