Katherine Heigl appears on The Late Show with David Letterman. She talks about Izzie and Grey's Anatomy.
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The shocking end of the season in which it is revealed that John Doe is George, and Izzie collapses.
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A terrific scene from the Grey's Anatomy season finale. It wasn't traditional, but this Meredith-Derek "wedding" was very romantic just the same.
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In yet another sneak preview of the Grey's Anatomy finale, Izzie gets some advice on what to do from a patient.
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Alex asks Derek what to do ... not as a doctor, but as a friend.
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In an emotional sneak preview of the Grey's Anatomy season finale, Izzie asks for a vote on what surgical route to take.
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Owen talks to Cristina about his mom. And how he hasn't seen her yet.
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Mark wants Lexie to move in with him in this preview of the season finale ... and sort of gets shot down.
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Grey's Anatomy Quotes

The first time I kissed my wife, she wasn't my wife then, she was just this girl in a bar. But when we kissed, it was like, I gotta tell you, it was like I'd never kissed any other woman before. It was like my first kiss. The right kiss.

Derek

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)