Why are so many people killing themselves? That's the question at the center of this Supernatural episode, as previewed here.
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Sam and Dean scout on a few vampires in this clip from "Live Free Or Twi-hard." As the title suggests, this episode plays off the vampire craze in Hollywood.
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Dean is bitten and turned into a vampire on this episode. Seriously! Check out the official promo for "Live Free or Twi-hard."
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A hunter has a body problem in this clip from Supernatural. Bobby is the only one who can help him.
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Bobby needs help on this episode of Supernatural. Check out the official preview for it now.
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Castiel is back on the episode "The Third Man." Check out this clip from the 10/8/10 episode of the show.
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Check out the official promo for The Third Man. On the episode, Sam and Dean call on Castiel for assistance as they investigate a case about several dead police officers.
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Sam threatens Dean with a "drive-by" in this clip from Supernatural. It's a nice tease for the episode "Two and a Half Men."
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Supernatural Quotes

Dean: So you’re saying we’re both a couple of dumbasses.
Cas: I prefer the word trusting. Less dumb, less ass.

You betrayed me? No one in the history of torture's been tortured with torture like the torture you'll be tortured with.

Crowley