To help listen to each other's problems in "Let the Angels Commit," George pretends to be Cristina and Meredith pretends to be Izzie... with humorous results.
[narrating] "To make it -- really make it -- as a surgeon, it takes major commitment. We have to be willing to pick up that scalpel and make a cut that may or may not do more damage than good. It's all about being committed, because if we're not? We have no business picking up that scalpel in the first place."