The print edition of TV Guide has some interesting tidbits on the next new episode of Grey's Anatomy, "I Will Follow You Into the Dark," airing March 12 ...

"Just when it seems that Derek and Meredith are en the road to happiness, he suffers a breakdown at the hospital. According to an insider, 'We've never seen him this way before, and it has the whole hospital concerned.' Shaken, he decides to resign.

As Derek Shepherd struggles with his issues, Mark Sloan steps in and is awarded the opportunity to perform a rare and delicate face-transplant surgery.

As for Izzie, the time has come to diagnose exactly what's wrong with her and it's not good. You'll be surprised whom she chooses to confide in first."

Also, the magazine's Q&A has the following exchange:

Q: Does T.R. Knight want Grey's Anatomy because he feels dwarfed by Patrick Dempsey?

A: Knight is staying mum, but who wouldn't feel that way? Dempsey's got his own cologne, for goodness sake. But there's another doctor at Seattle Grace who feels so overshadowed by Derek that he is not so affectionately known as "Shadow Shepherd." We'll meet the hospital's No. 2 neurosurgeon, Dr. Nelson (played by 49-year-old Phil Abrams), on March 12.

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.