James Pickens, Jr.: Katherine Heigl, T.R. Knight to Leave Grey's Anatomy Cast This Season

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Here we go again.

The ongoing soap opera concerning Grey's Anatomy stars Katherine Heigl and T.R. Knight and their uncertain futures took another crazy turn today when their co-star, James Pickens, Jr., commented that both of them are indeed leaving the show.

"Yes, she is," Pickens said when asked if the former Emmy winner was checking out of Seattle Grace. "Wherever Katherine goes, I wish her nothing but the best."

And what about T.R. Knight? "He's going too," Pickens, who plays Dr. Richard Webber, Chief of Surgery, said. "He just wanted to pursue other career paths."

BFFs Past and Present

ABC isn't commenting, but according to Entertainment Weekly, sources close to the situation have said regarding Pickens' comments, he may have jumped the gun.

While it's true Heigl and Knight want out, ABC execs have yet to officially issue the actors - who are under contract for six seasons - any Get Out of Jail Free cards.

However, all indications are that it will happen. The only question is when.

"Right now, the whole thing is in the hands of their agents and ABC's lawyers," explains a Grey's Anatomy insider. "Something will probably be worked out soon."

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.

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Grey's Anatomy Quotes

MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."

Arizona: Oh my God! I mean, I understand why you're into her. She's hot. Wait, she likes you?
Nathan: What? I mean, I'm going to try not to be offended at that.
Arizona: No, no, no. It's just that Derek was, Derek was epic for her. They were the great love story. I mean, that girl's heart beat for Derek Shepherd. It just, it never occurred to me that she would ever be with anyone else. He was perfect. He was everything. That man turned her world. It, I spooked you. Don't be spooked.